CAJ | 학술논문

1例因骨痛-行走困难-假骨折就诊的低磷性骨软化症患者。生化检查示血磷低、碱性磷酸酶高；影像学检查示：胸片肋骨多发骨折；胸腰椎及骨盆片腰椎骨质明显稀疏，呈双凹畸形，右耻骨上支假骨折。确诊为低磷性骨软化症，给予中性磷溶液、骨化三醇及钙尔奇D治疗2年后，生化指标改善、假性骨折愈合。临床上，对于该类疾病容易引起误诊或漏诊，上述药物的治疗时间、剂量应适当，否则会引起三发性甲状旁腺功能亢进症或疗效欠佳。
1례인골통-행주곤난-가골절취진적저린성골연화증환자。생화검사시혈린저、감성린산매고；영상학검사시：흉편륵골다발골절；흉요추급골분편요추골질명현희소，정쌍요기형，우치골상지가골절。학진위저린성골연화증，급여중성린용액、골화삼순급개이기D치료2년후，생화지표개선、가성골절유합。림상상，대우해류질병용역인기오진혹루진，상술약물적치료시간、제량응괄당，부칙회인기삼발성갑상방선공능항진증혹료효흠가。
A 47-year-old Chinese man with hypophosphatemic osteomalacia suffered from bone pain, difficulty in walking and pseudo-fractures. Biochemical examination showed a lowered serum phosphorus level and an elevated alkaline phosphatase level. The X-ray examination showed pseudo-fractures of multiple ribs, low bone density, biconcave deformities of the lumbar vertebrae, and pseudo-fracture of the right superior ramus of the pubis. A diagnosis of hypophosphatemic osteomalacia was made. The case was treated with oral neutral phosphate solution, calcitriol and Caltrate D. After treatment for two years, biochemical indicators were improved, and pseudo-fractures healed. Clinically, hypophosphatemic osteomalacia is often overlooked or misdiagnosed. In addition, the duration and dosage of these drugs should be appropriate, in order to avoid tertiary hyperparathyroidism or poor response to treatment.