CAJ | 학술논문

目的：探讨老年男性血清抵抗素水平与外周动脉硬化闭塞症（PAOD ）的关系。方法选择843例老年男性患者，分为 PAOD组165例和非PAOD组678例。检测血清抵抗素及C反应蛋白水平，进行相关分析。结果PAOD组血清抵抗素水平明显高于非PAOD组[（7．26±2．94）ng/L vs （6．49±3．09）ng/L ，P＜0．05]。血清抵抗素水平与C反应蛋白和 HDL-C独立相关（β＝0．058，β＝-0．810，P＜0．05）。抵抗素是 PAOD的独立危险因素（P＝0．004）。结论老年男性PAOD患者血清抵抗素水平升高，血清抵抗素水平可能是PAOD发病的预测因素。
목적：탐토노년남성혈청저항소수평여외주동맥경화폐새증（PAOD ）적관계。방법선택843례노년남성환자，분위 PAOD조165례화비PAOD조678례。검측혈청저항소급C반응단백수평，진행상관분석。결과PAOD조혈청저항소수평명현고우비PAOD조[（7．26±2．94）ng/L vs （6．49±3．09）ng/L ，P＜0．05]。혈청저항소수평여C반응단백화 HDL-C독립상관（β＝0．058，β＝-0．810，P＜0．05）。저항소시 PAOD적독립위험인소（P＝0．004）。결론노년남성PAOD환자혈청저항소수평승고，혈청저항소수평가능시PAOD발병적예측인소。
Abstratct:Objective To study the relation between serum resistin level and peripherial arterial occlusive disease (PAOD) in elderly males .Methods Eight hundred and forty-three elderly male patients were divided into PAOD group (n=165) and non-PAOD group (n=678) .Their serum levels of resistin and CRP were mesured and analyzed by correlation analysis .Results The serum resistin level was significantly higher in PAOD group than in non-PAOD group (7 .26 ± 2 .94 ng/L vs 6 .49 ± 3 .09 ng/L ,P<0.05) and independlty related with the serum CRP and HDL-C level (P<0 .05) .The incidence of PAOD increased with the serum resistin level ,indicating that resistin was an independent risk factor for PAOD .Conclusion Serum resistin level is significantly higher in elderly male PAOD patients and may be a predictive factor for PAOD .