CAJ | 학술논문

肌少症，亦称骨骼肌减少症（sarcopenia）或者说是增龄性骨骼肌减少，是以骨骼肌质量、力量以及功能的降低为主要特征的退行性综合征。肌少症的发生机制复杂多样，包括运动量下降、神经-肌肉功能衰退及运动单位重组、蛋白质摄入与合成减少、激素水平变化、脂肪组织增加与慢性炎症反应、细胞凋亡、骨骼肌线粒体功能紊乱及基因与种族等。深入研究肌少症的发病机理对老年人肌少症的防治具有重要意义。
기소증，역칭골격기감소증（sarcopenia）혹자설시증령성골격기감소，시이골격기질량、역량이급공능적강저위주요특정적퇴행성종합정。기소증적발생궤제복잡다양，포괄운동량하강、신경-기육공능쇠퇴급운동단위중조、단백질섭입여합성감소、격소수평변화、지방조직증가여만성염증반응、세포조망、골격기선립체공능문란급기인여충족등。심입연구기소증적발병궤리대노년인기소증적방치구유중요의의。
Sarcopenia, also known as age-related sarcopenia,is defined as adegenerativesyndrome characterized by progressive and generalized loss of skeletal muscle mass, strength and function. Sarcopeniainvolves complex mechanisms, including exercise lacking, neuromuscular function decline and motor unit restructuring, declining in adequate protein intake and synthesis, changingin hormonelevels,expansionoffattissue and chronic inflammation, apoptosis, skeletal muscle mitochondrial dysfunction, and different genes and ethnics,et al.Further studyonthe mechanisms of sarcopeniais of greatsignificancein the prevention and treatment of geriatric sarcopenia.