CAJ | 학술논문

目的：对30例子宫富于细胞性平滑肌瘤（CUL）的临床及病理特点进行分析，探讨其生物学行为及临床结局，以指导临床诊断和治疗。方法回顾性分析了2008年1月至2013年1月在我院手术的30例CUL患者的临床病理资料，并对其进行了随访。结果大部分患者以月经改变为主要症状，超声检查以低回声团块多见，病理特点为瘤细胞丰富，细胞大小形态较一致，核分裂相0-4个/10HPF，细胞异型性不明显，无凝固性坏死,行全子宫切除无复发，行肌瘤剔除术复发率27.27%。结论 CUL的临床表现与普通的子宫平滑肌瘤相似，治疗宜行全子宫切除。对于有生育要求的年轻女性在保留子宫的同时应密切随诊。
목적：대30례자궁부우세포성평활기류（CUL）적림상급병리특점진행분석，탐토기생물학행위급림상결국，이지도림상진단화치료。방법회고성분석료2008년1월지2013년1월재아원수술적30례CUL환자적림상병리자료，병대기진행료수방。결과대부분환자이월경개변위주요증상，초성검사이저회성단괴다견，병리특점위류세포봉부，세포대소형태교일치，핵분렬상0-4개/10HPF，세포이형성불명현，무응고성배사,행전자궁절제무복발，행기류척제술복발솔27.27%。결론 CUL적림상표현여보통적자궁평활기류상사，치료의행전자궁절제。대우유생육요구적년경녀성재보류자궁적동시응밀절수진。
Objective To investigate clinicopathological characteristics, biological behavior and clinical outcome in 60 patients who had cellular uterine leiomyoma (CUL). Methods The pathological data from the 60 CUL patients who accepted operative treatment in our hospital during 2008-2013 were retrospectively collected. All patients were followed up. Results The main clini-cal symptom was menstrual changes. And B-Ultrasonography showed mostly hypoechoic mass. The pathological features included enriched smooth muscle cells. And karyokinetic division was seldom observed. There were 0-4 cells per 10 highpower field. The recurrence rate of CUL was 23.3% in patients who accepted myomectomy. No case recurred in patients who accepted hysterecto-my. Conclusion The clinical features of CUL are similar to ordinary uterine leiomyoma. Patients with CUL should be treated by hysterectomy.