CAJ | 학술논문

【目的】探讨青少年胃食管反流病（GERD）问卷评分（GERDQ ）与胃镜表现特点的关系。【方法】选择2010年1月至2014年1月在本院就诊的GERD患者51例，同一时期同科非GERD患者50例为对照组，并比较GERDQ与胃镜检查对GERD的诊断价值。【结果】患者的GERDQ评分分布情况结果显示GERD组患者GERDQ评分主要以8～11分为主，其所占患者比例达62．7％，对照组患者GERDQ评分以7～9分为主，所占患者比例达50．0％。GERD组胃镜检查阳性结果42例（82．4％），阴性结果9例（17．6％），对照组阴性结果36例（72．0％），阳性结果14例（28．0％）。根据GERDQ评分的ROC结果，取临界值7．5时，其诊断的敏感度和特异度最佳，分别为敏感度84．3％，特异度56．0％，阳性预测值66．6％，阴性预测值77．4％。【结论】青少年GERD的GERDQ评分及胃镜检查均有良好的诊断效果，其中GERDQ的青少年GERD诊断临界值为7．5，相对的胃镜表现以LA分级A ，B级为主，即青少年GRED病情普遍较轻。
【목적】탐토청소년위식관반류병（GERD）문권평분（GERDQ ）여위경표현특점적관계。【방법】선택2010년1월지2014년1월재본원취진적GERD환자51례，동일시기동과비GERD환자50례위대조조，병비교GERDQ여위경검사대GERD적진단개치。【결과】환자적GERDQ평분분포정황결과현시GERD조환자GERDQ평분주요이8～11분위주，기소점환자비례체62．7％，대조조환자GERDQ평분이7～9분위주，소점환자비례체50．0％。GERD조위경검사양성결과42례（82．4％），음성결과9례（17．6％），대조조음성결과36례（72．0％），양성결과14례（28．0％）。근거GERDQ평분적ROC결과，취림계치7．5시，기진단적민감도화특이도최가，분별위민감도84．3％，특이도56．0％，양성예측치66．6％，음성예측치77．4％。【결론】청소년GERD적GERDQ평분급위경검사균유량호적진단효과，기중GERDQ적청소년GERD진단림계치위7．5，상대적위경표현이LA분급A ，B급위주，즉청소년GRED병정보편교경。
To explore the questionnaire scores and gastroscopic findings of gastroesophageal reflux disease(GERD) in adolescents .[Methods]Totally 51 patients with GRED in our hospital from Jan . 2010 to Jan .2014 were chosen .Other 50 concurrent patients without GRED in the same department were cho-sen as the control group .The diagnostic critical value was calculated .The diagnostic value between question-naire scores of GERD(GERDQ) and gastroscopy of GERD was compared .[Results]The distribution result of GERDQ scores of patients showed that GERDQ in GERD group was mainly 8~11 scores which the proportion of patients was 62 .7% ,while that in control group was mainly 7~9 scores which the proportion of patients was 50 .0% .There were 42 patients with positive results of gastroscopy (82 .4% ) and 9 patients with negative results(17 .6% ) in GERD group ,while there were 14 patients with positive results (28 .0% ) and 36 patients with negative results (72 .0% ) in control group .According to ROC result pf GERDQ score ,the diagnostic sensitivity and specificity were the best when the critical value was 7 .5 .The sensitivity ,specificity ,positive predictive value and negative predictive value were 84 .3% ,56 .0% ,66 .6% and 77 .4% ,respectively .[Con-clusion]Both GERDQ score and gastroscopy for the diagnosis of GERD have good effect .If the critical value of GERDQ for the diagnosis of GERD was 7 .5 and the relative gastroscopic findings are mainly LA classifica-tion A and Band in adolescents ,the pathogenetic condition of GERD in adolescents is generally milder .