CAJ | 학술논문

目的：观察加味枳术颗粒对改善恶性肿瘤患者食欲的临床疗效。方法将120例患者按照随机对照方法分为治疗组(加味枳术颗粒组)、对照组(醋酸甲地孕酮片组)各60例，自然脱落5例，最终进入数据统计的为治疗组58例，对照组57例，两组均连续治疗4周，观察治疗前后食欲NRS评分、生活质量KPS评分变化。结果治疗组与对照组NRS评分有效率分别为67%、65%，两组比较差异无显著性(P>0.05)；KPS评分治疗组与对照组有效率分别为67%、58%，两组比较差异有显著性(P<0.05)。结论加味枳术颗粒可改善肿瘤患者的食欲，其临床疗效与醋酸甲地孕酮相当；在改善患者生活质量方面，加味枳术颗粒优于醋酸甲地孕酮。
목적：관찰가미지술과립대개선악성종류환자식욕적림상료효。방법장120례환자안조수궤대조방법분위치료조(가미지술과립조)、대조조(작산갑지잉동편조)각60례，자연탈락5례，최종진입수거통계적위치료조58례，대조조57례，량조균련속치료4주，관찰치료전후식욕NRS평분、생활질량KPS평분변화。결과치료조여대조조NRS평분유효솔분별위67%、65%，량조비교차이무현저성(P>0.05)；KPS평분치료조여대조조유효솔분별위67%、58%，량조비교차이유현저성(P<0.05)。결론가미지술과립가개선종류환자적식욕，기림상료효여작산갑지잉동상당；재개선환자생활질량방면，가미지술과립우우작산갑지잉동。
Objective To Observe the clinical effects of jiaweizhizhu particles on improving the malignant tumor pa-tients appetite. Method 120 Malignant tumor patients are randomized equally into two groups: the treatment group (60 cases) received jiaweizhizhu particles and the control group (60 cases) received megestrol. Five cases fall off naturally, Finally enter the data statistics of 58 cases for treatment group, control group of 57 cases . The treatment lasts 4 weeks. The therapeutic effect is evaluated after treatment and the changes of appetite NRS and KPS are ob-served before and after treatment. Result NRS score efficient in treatment group and control group are 67% 、65%, which has no statistical significance(P>0. 05). KPS score efficient in treatment group and control group are 67%、58%,which has statistical significance(P<0. 05). Conclusion jiawei-zhizhu particles can improve the appetite of cancer patients, its clinical curative effect, compared with megestrol, does not have obvious difference. On impro-ving life quality, jiaweizhizhu particles is superior to megestrol.