Notch通路及维甲酸与肾纤维化研究进展
Notch통로급유갑산여신섬유화연구진전
Notch Signaling in Renal Interstitial Fibrosis and Retinoic Acid
  • 万方数据
    天津医药 천진의약
    TIANJIN MEDICAL JOURNAL
    2014年 9期 956-960 ,共5页

    杜轩%涂卫平

    두헌%도위평

    维甲酸%Notch信号%肾间质纤维化 維甲痠%Notch信號%腎間質纖維化
    유갑산%Notch신호%신간질섬유화
    retinoic acid%Notch signaling%renal interstitial fibrosis
    维甲酸（RA）对肾间质纤维化(RIF)存在着重要的影响，Notch信号途径在肾纤维化中发挥了关键作用，本文就维甲酸对肾纤维化与Notch通路的影响进行综述，探索维甲酸干预Notch途径能否成为新的抗肾纤维化策略。
    유갑산（RA）대신간질섬유화(RIF)존재착중요적영향，Notch신호도경재신섬유화중발휘료관건작용，본문취유갑산대신섬유화여Notch통로적영향진행종술，탐색유갑산간예Notch도경능부성위신적항신섬유화책략。
    The effect of retinoic acid (RA) on renal interstitial fibrosis (RIF) is important. Notch signaling is known to play an important role in the pathological injury of RIF. This study summarized recent research progress of the effect of RA on RIF and Notch signaling. Interruption of Notch signaling by RA might be a potential anti-fibrotic strategy in RIF.
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