中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2014年
4期
552-555
,共4页
脑卒中,重症%多药耐药菌%医院感染
腦卒中,重癥%多藥耐藥菌%醫院感染
뇌졸중,중증%다약내약균%의원감염
Severe stroke disease%Multidrug-resistant bacteria%Nosocomial infection
目的：调查重症脑卒中患者多药耐药菌的感染情况，为预防和控制多药耐药菌的感染提供科学依据。方法对2010年1月至2013年10月本科室收治的92例并发多药耐药菌感染的重症脑卒中患者临床资料和病原菌感染情况，采用回顾性方法进行分析。结果本科室重症脑卒中患者并发多药耐药菌感染率为3.59%（92/2564），共分离培养多药耐药菌株92株，依次为产超广谱β-内酰胺酶肺炎克雷伯菌、大肠埃希菌、耐甲氧西林金黄色葡萄球菌、铜绿假单胞菌和鲍曼不动杆菌，分别占48.91%（45/92）、33.69%（31/92）、6.52%（6/92）、5.43%（5/92）和3.26%（3/92）。感染标本主要来自痰液和尿液，分别占44.57%（41/92）和31.52%（29/92）。结论对重症脑卒中并发多药耐药菌感染的患者，应针对引发耐药菌株产生的薄弱环节，加强监测，并采取切实、有效措施，预防和控制多药耐药菌感染的发生。
目的：調查重癥腦卒中患者多藥耐藥菌的感染情況，為預防和控製多藥耐藥菌的感染提供科學依據。方法對2010年1月至2013年10月本科室收治的92例併髮多藥耐藥菌感染的重癥腦卒中患者臨床資料和病原菌感染情況，採用迴顧性方法進行分析。結果本科室重癥腦卒中患者併髮多藥耐藥菌感染率為3.59%（92/2564），共分離培養多藥耐藥菌株92株，依次為產超廣譜β-內酰胺酶肺炎剋雷伯菌、大腸埃希菌、耐甲氧西林金黃色葡萄毬菌、銅綠假單胞菌和鮑曼不動桿菌，分彆佔48.91%（45/92）、33.69%（31/92）、6.52%（6/92）、5.43%（5/92）和3.26%（3/92）。感染標本主要來自痰液和尿液，分彆佔44.57%（41/92）和31.52%（29/92）。結論對重癥腦卒中併髮多藥耐藥菌感染的患者，應針對引髮耐藥菌株產生的薄弱環節，加彊鑑測，併採取切實、有效措施，預防和控製多藥耐藥菌感染的髮生。
목적：조사중증뇌졸중환자다약내약균적감염정황，위예방화공제다약내약균적감염제공과학의거。방법대2010년1월지2013년10월본과실수치적92례병발다약내약균감염적중증뇌졸중환자림상자료화병원균감염정황，채용회고성방법진행분석。결과본과실중증뇌졸중환자병발다약내약균감염솔위3.59%（92/2564），공분리배양다약내약균주92주，의차위산초엄보β-내선알매폐염극뢰백균、대장애희균、내갑양서림금황색포도구균、동록가단포균화포만불동간균，분별점48.91%（45/92）、33.69%（31/92）、6.52%（6/92）、5.43%（5/92）화3.26%（3/92）。감염표본주요래자담액화뇨액，분별점44.57%（41/92）화31.52%（29/92）。결론대중증뇌졸중병발다약내약균감염적환자，응침대인발내약균주산생적박약배절，가강감측，병채취절실、유효조시，예방화공제다약내약균감염적발생。
Objective To investigate the status of multidrug-resistant bacteria infections in patients with severe stroke diseases, and provide scientific basis for the prevention and control of the multidrug-resistant bacteria infections. Methods A total of 92 cases with multidrug-resistant bacteria infections and severe stroke from January 2010 to October 2013 were enrolled, then the clinical data and the situation of pathogenic bacteria infections were analyzed, retrospectively. Results In our department, the rate of multidrug-resistant bacteria infections with severe stroke diseases was 3.59% (92/2 564). A total of 92 strains of pathogens were isolated, among which the most was producing extended spectrum beta lactamases Klebsiella pneumoniae, followed by Escherichia coli, methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Acinetobacter baumannii, accounting for 48.91% (45/92), 33.69% (31/92), 6.52%(6/92), 5.43%(5/92) and 3.26%(3/92), respectively. Infected samples were mainly from sputum and urine, accounting for 44.57%(41/92) and 31.52%(29/92). Conclusions For the patients with severe stroke complicating multidrug-resistant bacteria infections, it is should lead to resistant strains against the weak links, strengthen the monitoring, and taking practical, effective measures, so as to prevent and control the multidrug-resistant bacteria infections.
