中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2014年
4期
507-509
,共3页
流行性乙型脑炎%氧化还原态
流行性乙型腦炎%氧化還原態
류행성을형뇌염%양화환원태
Epidemic encephalitis B%Oxidation-reduction
目的：探讨流行性乙型脑炎患者机体氧化还原态。方法选取40例流行性乙型脑炎患儿为研究对象，分别测定发病极期和恢复期血浆还原型谷胱甘肽（GSH）与氧化型谷胱甘肽（GSSG），还原型辅酶Ⅱ（NADPH）与氧化型辅酶Ⅱ（NADP+），计算GSH/GSSG和NADPH/NADP+比值，评价HIV/AIDS患者机体氧化还原态。结果流行性乙型脑炎患儿发病极期血浆氧化还原态向氧化方向偏移。结论氧化还原态失衡、氧化还原态向氧化方向偏移与流行性乙型脑炎疾病进展有一定相关性。
目的：探討流行性乙型腦炎患者機體氧化還原態。方法選取40例流行性乙型腦炎患兒為研究對象，分彆測定髮病極期和恢複期血漿還原型穀胱甘肽（GSH）與氧化型穀胱甘肽（GSSG），還原型輔酶Ⅱ（NADPH）與氧化型輔酶Ⅱ（NADP+），計算GSH/GSSG和NADPH/NADP+比值，評價HIV/AIDS患者機體氧化還原態。結果流行性乙型腦炎患兒髮病極期血漿氧化還原態嚮氧化方嚮偏移。結論氧化還原態失衡、氧化還原態嚮氧化方嚮偏移與流行性乙型腦炎疾病進展有一定相關性。
목적：탐토류행성을형뇌염환자궤체양화환원태。방법선취40례류행성을형뇌염환인위연구대상，분별측정발병겁기화회복기혈장환원형곡광감태（GSH）여양화형곡광감태（GSSG），환원형보매Ⅱ（NADPH）여양화형보매Ⅱ（NADP+），계산GSH/GSSG화NADPH/NADP+비치，평개HIV/AIDS환자궤체양화환원태。결과류행성을형뇌염환인발병겁기혈장양화환원태향양화방향편이。결론양화환원태실형、양화환원태향양화방향편이여류행성을형뇌염질병진전유일정상관성。
Objective To investigate the redox status in patients with epidemic encephalitis B. Methods Plasma glutathione (reduced form GSH and oxidized form GSSG) were measured by fluorescence spectrophotometry, reduced form NADPH and oxidized form NADP+ were measured by UV spectrophotometry in very period and recovery time. Redox status was evaluated by GSH/GSSG and NADPH/NADP+. Results The GSH/GSSG and NADPH/NADP+ redox status in plasma of patients deviated to pro-oxidative direction in the critical stage. Conclusions The imbanlance and deviation to prooxidative direction of redox status closely related with the occurrence and development of epidemic encephalitis B.
