CAJ | 학술논문

目的：通过观察2011年1月至2013年10月共11个季度的肺炎链球菌耐药的情况，指导临床工作。方法对11个季度的肺炎链球菌耐药情况进行统计。结果在目前临床上常用的抗菌素中，二代头孢菌素(头孢呋辛)耐药率为33．0%、头孢曲松为6．0%、头孢噻肟为20．3%、阿莫西林/棒酸为0．1%、克林霉素为84．0%，作为经典的抗肺炎链球菌的青霉素，其耐药率为95．0%，而红霉素的耐为99．0%。结论肺炎链球菌作为社区获得性肺炎( CAP)的主要致病菌，耐药情况总体很不乐观，经典的抗菌素中，青霉素和红霉素几近无效。目前临床常用抗菌素中，对肺炎链球菌耐药率低的品种并不多，因此，规范、合理地使用好现有的抗菌素就显得尤为重要。
목적：통과관찰2011년1월지2013년10월공11개계도적폐염련구균내약적정황，지도림상공작。방법대11개계도적폐염련구균내약정황진행통계。결과재목전림상상상용적항균소중，이대두포균소(두포부신)내약솔위33．0%、두포곡송위6．0%、두포새우위20．3%、아막서림/봉산위0．1%、극림매소위84．0%，작위경전적항폐염련구균적청매소，기내약솔위95．0%，이홍매소적내위99．0%。결론폐염련구균작위사구획득성폐염( CAP)적주요치병균，내약정황총체흔불악관，경전적항균소중，청매소화홍매소궤근무효。목전림상상용항균소중，대폐염련구균내약솔저적품충병불다，인차，규범、합리지사용호현유적항균소취현득우위중요。
Objective To instruct clinical work through observing condition of Streptococcus pneumoniae drug resistance from 11 quarters of January 2011 to October 2013. Methods To collect the condition of Streptococcus pneumoniae drug resist-ance of 11 quarters. Results In antibiotics used clinically often now,drug resistant ratio of the 2rd generation cephalosporin(Ce-furoxime)is 33%,ceftriaxone is 6%,cefotaxime is 20. 3%,Amoxicillin/clavulanic acid is 0. 1%,clindamycin is 84%,Penicillin as a classic antibiotic,its drug resistant ratio is 95%,and erythromycin is 99%. Conclusion Streptococcus pneumoniae as a ma-jor pathogenic bacteria of CAP,its total condition of drug resistance is not very optimistical,in classic antibiotics,Penicillin and e-rythromycin is nearly inefficacious. In antibiotics used clinically often now,the species that its drug resistant ratio is low to Strepto-coccus pneumoniae is modicus. Accordingly,it is very important to use the existing antibiotics normatively and reasonably.