CAJ | 학술논문

目的：比较使用胸腺五肽前后患者外周血血小板数目上升的情况。方法同期将40例病毒感染相关性血小板减少症患者随机分为2组,1组给予胸腺五肽肌肉注射,1组给予低剂量糖皮质激素(20mg/d)联合升血小板胶囊口服,用药7d,14d,21d,28d后观察比较患者外周血血小板上升情况。结果胸腺五肽治疗组用药14d血小板数目明显上升,16例患者用药28d血小板上升至30×109/L以上,对照组用药28d的过程中血小板数目无明显改变。结论胸腺五肽可通过免疫调节作用有效治疗病毒感染相关性血小板减少。
목적：비교사용흉선오태전후환자외주혈혈소판수목상승적정황。방법동기장40례병독감염상관성혈소판감소증환자수궤분위2조,1조급여흉선오태기육주사,1조급여저제량당피질격소(20mg/d)연합승혈소판효낭구복,용약7d,14d,21d,28d후관찰비교환자외주혈혈소판상승정황。결과흉선오태치료조용약14d혈소판수목명현상승,16례환자용약28d혈소판상승지30×109/L이상,대조조용약28d적과정중혈소판수목무명현개변。결론흉선오태가통과면역조절작용유효치료병독감염상관성혈소판감소。
Objective The number of platelets in peripheral blood before and after thymus peptide using outer rise situa-tion. Methods Over the same period,40 cases of virus infection associated thrombocytopenia patients were randomly divided into 2 groups,The 1 group received intramuscular injection of five thymus peptide,The 1 group received low doses of Glucocorticoid (20mg/d)combined with shengxuexiaoban capsule,After 7 days,14 days,21 days,28 days of observation and comparison of plate-lets in peripheral blood of patients with increased. Results Five thymus peptide drug treatment group 14 days platelet count in-creased significantly,16 patients after 28 days of platelet increased to 30 × 10/L,the number of platelet process control group 28 days no significant change. Conclusion Five thymus peptide can reduce correlation immune platelet function is effective in the treatment of viral infection control.