CAJ | 학술논문

目的：观察莫西沙星治疗急性盆腔炎临床效果,探讨其应用价值。方法选择2007年1月至2012年1月急性盆腔炎患者92例作为研究对象,随机分成观察组及对照组各46例,观察组给予莫西沙星400mg/d,先静脉给药3d,待病情好转(改善)或体温正常后8h,改为口服,剂量不变,疗程14d；对照组左氧氟沙星300mg+甲硝唑500mg,静滴,每日1次,共14d。结果观察组总有效率95．65%高于对照组的76．05%；临床症状改善时间(3．05±1．67) d、静脉给药时间(6．78±1．23)d、住院时间(9．12±1．56)d均短于对照组的(4．82±2．01)d、(14．00±0．00)d、(17．98±2．67)d(P<0．05)。观察组药物不良反应6．52%低于对照组的23．91%。结论莫西沙星单药治疗与左氧氟沙星加甲硝唑联合治疗方案相比,临床疗效高,发生不良反应低,值得临床应用。
목적：관찰막서사성치료급성분강염림상효과,탐토기응용개치。방법선택2007년1월지2012년1월급성분강염환자92례작위연구대상,수궤분성관찰조급대조조각46례,관찰조급여막서사성400mg/d,선정맥급약3d,대병정호전(개선)혹체온정상후8h,개위구복,제량불변,료정14d；대조조좌양불사성300mg+갑초서500mg,정적,매일1차,공14d。결과관찰조총유효솔95．65%고우대조조적76．05%；림상증상개선시간(3．05±1．67) d、정맥급약시간(6．78±1．23)d、주원시간(9．12±1．56)d균단우대조조적(4．82±2．01)d、(14．00±0．00)d、(17．98±2．67)d(P<0．05)。관찰조약물불량반응6．52%저우대조조적23．91%。결론막서사성단약치료여좌양불사성가갑초서연합치료방안상비,림상료효고,발생불량반응저,치득림상응용。
Objective To observe the clinical effect of moxifloxacin treatment of acute pelvic inflammatory disease,to ex-plore the application value. Methods Select January 2007 to January 2012 acute pelvic inflammatory disease 92 patients as the research object,randomly divided into observation group and control group each 46 case,the observation group were given moxi-floxacin 400mg/d,first intravenous administration of 3d,to be better(improve) or normal body temperature after 8h,changed to o-ral,constant dose,duration 14d,the control groupLevofloxacin 300mg+ metronidazole 500mg,intravenous drip,1 times daily,14D. Results Total effective rate of observation group 95. 65% is higher than the control group 76. 05%;the clinical symptoms im-proved time(3. 05 ± 1. 67)d,intravenous administration time(6. 78 ± 1. 23)d,hospitalization time(9. 12 ± 1. 56 d are shorter than the control group(4. 82 ±2. 01)d,(14. 00 ±0. 00)d,(17. 98 ±2. 67)d(P<0. 05). Observation group adverse reaction of drugs 6. 52% lower than that of the control group 23. 91%. Conclusion Moxifloxacin monotherapy compared with the combination therapy of moxifloxacin monotherapy and left of loxacin Clinical efficacy, adverse reactions,it is worthy of clinical application.