CAJ | 학술논문

建立了液相色谱质谱联用法同时测定酒中污染物23种邻苯二甲酸酯类增塑剂残留量的检测方法。样品经过沸水加热除去乙醇后，正己烷提取，经Waters ACQUITY UPLC? BEH C18色谱柱分离，以甲醇和0.1%甲酸溶液为流动相梯度洗脱，电喷雾正离子模式离子化，选择反应监测方式监测，串联质谱测定，外标法定量。结果显示，各目标物在0.1～10.0 mg/L浓度范围内的线性关系良好，相关系数大于0.993。该方法对酒中23种邻苯二甲酸酯化合物的定量限为0.1 mg/kg，23种邻苯酸二甲酸酯的回收率为87%～102%。结果表明，该方法简便快速、灵敏可靠、经济有效，适用于酒中污染物邻苯二甲酸酯检测的需要。
건립료액상색보질보련용법동시측정주중오염물23충린분이갑산지류증소제잔류량적검측방법。양품경과비수가열제거을순후，정기완제취，경Waters ACQUITY UPLC? BEH C18색보주분리，이갑순화0.1%갑산용액위류동상제도세탈，전분무정리자모식리자화，선택반응감측방식감측，천련질보측정，외표법정량。결과현시，각목표물재0.1～10.0 mg/L농도범위내적선성관계량호，상관계수대우0.993。해방법대주중23충린분이갑산지화합물적정량한위0.1 mg/kg，23충린분산이갑산지적회수솔위87%～102%。결과표명，해방법간편쾌속、령민가고、경제유효，괄용우주중오염물린분이갑산지검측적수요。
The residual quantity of 23 kinds of p hthalate esters in liquor was measured simultaneously by UPLC-MS. Firstly, liquor sample was heated by boiling water to remove ethanol, then extracted with n-hexane, and then isolated by centrifugation, the separation was perfomed on a Waters ACQUITY UPLC? BEH C18 column with aradient elution using methanol and 0.1%formic acid, and the electrospray ionization (ESI) source in positive ion mode was used for multiple reaction monitoring (RSM), then tandem MS was used for the measurement, and the external standard method was used for the quantification.The measurement results suggested that, the linear relationship of each phthalate ester was good within the range between 0.1~10.0 mg/kg and the correlation coefficient was above 0.993. The detection limits of such method were 0.1~0.5 mg/kg. The recoveries of 23 kinds of phthalate esters were ranged from 87.5%~101.2%with the relative standard deviations of 1.7%~5.8%. Such method was easy,fast,sensitive,and suitable for the determination of 23 kinds of phalate esters in liquor samples.