CAJ | 학술논문

目的：比较丙泊酚与依托咪酯对全麻诱导期间血流动力学的变化和围麻醉期不良反应。方法选择全麻下行腹部手术患者100例,随机分为丙泊酚组(P组)和依托咪酯组(E组),P组静脉给予咪达唑仑-丙泊酚-芬太尼-罗库溴铵诱导,E组用依托咪酯替换P组丙泊酚。观察两组患者诱导前(T0)、插管前(T1)、插管后3 min(T2)循环、应激和其他不良反应。结果组间比较,T1 SBP和HR、T2SBP、DBP和HR, E组大于P组,注射痛P组多于E组,肌颤E组多于P组,差异均有统计学意义(P<0.05)。结论依托咪酯更适用于循环功能不稳定者；两者对血糖均无影响。
목적：비교병박분여의탁미지대전마유도기간혈류동역학적변화화위마취기불량반응。방법선택전마하행복부수술환자100례,수궤분위병박분조(P조)화의탁미지조(E조),P조정맥급여미체서륜-병박분-분태니-라고추안유도,E조용의탁미지체환P조병박분。관찰량조환자유도전(T0)、삽관전(T1)、삽관후3 min(T2)순배、응격화기타불량반응。결과조간비교,T1 SBP화HR、T2SBP、DBP화HR, E조대우P조,주사통P조다우E조,기전E조다우P조,차이균유통계학의의(P<0.05)。결론의탁미지경괄용우순배공능불은정자；량자대혈당균무영향。
Objective To observe the effect of propofol and etomidate for anesthesia induction on hemodynamics and adverse reactions during the perioperative period. Methods One hundred patients undergoing elective abdominal surgery were randomly divided into the propofol group (Group P) and etomidate group(Group E). For anesthesia induc-tion, successively injected midazolam-propofol-fentanyl-rocuronium in Group P, and the propofol was replaced by eto-midate in Group P. The circulation,stress and the adverse reactions before induction(T0), before intubation(T1), 3 min after intubation (T2), two groups were recorded. Results Compared with the P group, the T1 SBP, HR, T2 SBP, DBP, and HR were higer in E group; The incidence of injection pain was higher in Group P , but the incidence of muscle tremors was lower in Group P(P<0.05). Conclusion The etomidate is more suitable for the patients with hemodynamic instability. Both etomidate and propofol has no effect on blood sugar.