CAJ | 학술논문

目的：探讨对老年危重症急性肾损伤患者进行连续性血液净化的治疗效果。方法：将2012年1月-2014年1月的140例于本院ICU监护病房住院治疗的老年危重症急性肾损伤患者作为研究对象，按照随机双盲对照分配的原则分为观察组和对照组，其中对照组患者主要给予常规的老年危重症急性肾损伤治疗措施，而观察组患者在对照组治疗措施的基础上辅以连续性的血液净化治疗，观察两组患者的治疗效果及各项化验结果的变化。结果：观察组患者治疗后的系统评分和对照组相比显著降低，差异具有统计学意义（P<0.05）；观察组患者各项指标（动脉血气pH值、尿素氮、HCO3-、血肌酐、电解质）均优于对照组（P<0.05）。结论：对老年危重症急性肾损伤患者在常规治疗的基础上辅以连续性的血液净化治疗，不仅可以显著提高患者的临床治愈率，而且能够显著改善机体内环境的紊乱，值得推广。
목적：탐토대노년위중증급성신손상환자진행련속성혈액정화적치료효과。방법：장2012년1월-2014년1월적140례우본원ICU감호병방주원치료적노년위중증급성신손상환자작위연구대상，안조수궤쌍맹대조분배적원칙분위관찰조화대조조，기중대조조환자주요급여상규적노년위중증급성신손상치료조시，이관찰조환자재대조조치료조시적기출상보이련속성적혈액정화치료，관찰량조환자적치료효과급각항화험결과적변화。결과：관찰조환자치료후적계통평분화대조조상비현저강저，차이구유통계학의의（P<0.05）；관찰조환자각항지표（동맥혈기pH치、뇨소담、HCO3-、혈기항、전해질）균우우대조조（P<0.05）。결론：대노년위중증급성신손상환자재상규치료적기출상보이련속성적혈액정화치료，불부가이현저제고환자적림상치유솔，이차능구현저개선궤체내배경적문란，치득추엄。
Objective: To explore the clinical effect of continuous blood purification treated in elderly critically acute kidney injury patients.Method: 140 elderly critically acute kidney injury patients were selected form ICU in our hospital during January 2012 and January 2014, who were divided into observation group and control group by randomly and double-blind principles. The control group was treated by conventional elderly critically acute kidney injury treatment, and observation group was adopted continuous blood purification beside the conventional elderly critically acute kidney injury treatment. We compared the treatment effects and test results between the two groups.Result:The observation group was better than the control group in system test scores after treatment, and the difference was significantly(P<0.05). In various indicators (such as arterial blood gas pH, blood urea nitrogen, HCO3-, serum creatinine, electrolytes), the observation group was better than the control group, and the difference was significant(P<0.05). Conclusion: Continuous blood purification beside the conventional elderly critically acute kidney injury treatment can improve the clinical cure rate and the disorder of body internal environment, so it is worth to promote in clinical.