中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
25期
30-32
,共3页
视网膜母细胞瘤%放射治疗%手术%临床观察
視網膜母細胞瘤%放射治療%手術%臨床觀察
시망막모세포류%방사치료%수술%림상관찰
Retinoblastoma%Radiotherapy%Operation%Clinical observation
目的：探讨视网膜母细胞瘤手术联合放疗的临床效果。方法：选取2009年1月-2012年6月的100例视网膜母细胞瘤患者，在患者知情同意的前提下，分为两组，观察组50例在术后均接受放射治疗，对照组50例仅给予常规手术治疗。随访2年以上，统计两组患者1年、2年生存率及复发转移率。结果：两组术后随访24~60个月，平均随访（43.89±5.39）个月。观察组术后1年生存率为100%，对照组为88%，观察组明显高于对照组，差异具有统计学意义（P<0.05）。观察组术后1年复发转移率为2%，对照组为18%，观察组明显低于对照组，差异具有统计学意义（P<0.05）。观察组术后2年生存率为98%，对照组为80%，观察组明显高于对照组，差异具有统计学意义（P<0.05）。观察组术后2年复发转移率为8%，对照组为24%，观察组明显低于对照组，差异具有统计学意义（P<0.05）。结论：术后放疗在视网膜母细胞瘤的治疗中起到重要作用，可达到控制肿瘤复发转移、提高生存率的目的。
目的：探討視網膜母細胞瘤手術聯閤放療的臨床效果。方法：選取2009年1月-2012年6月的100例視網膜母細胞瘤患者，在患者知情同意的前提下，分為兩組，觀察組50例在術後均接受放射治療，對照組50例僅給予常規手術治療。隨訪2年以上，統計兩組患者1年、2年生存率及複髮轉移率。結果：兩組術後隨訪24~60箇月，平均隨訪（43.89±5.39）箇月。觀察組術後1年生存率為100%，對照組為88%，觀察組明顯高于對照組，差異具有統計學意義（P<0.05）。觀察組術後1年複髮轉移率為2%，對照組為18%，觀察組明顯低于對照組，差異具有統計學意義（P<0.05）。觀察組術後2年生存率為98%，對照組為80%，觀察組明顯高于對照組，差異具有統計學意義（P<0.05）。觀察組術後2年複髮轉移率為8%，對照組為24%，觀察組明顯低于對照組，差異具有統計學意義（P<0.05）。結論：術後放療在視網膜母細胞瘤的治療中起到重要作用，可達到控製腫瘤複髮轉移、提高生存率的目的。
목적：탐토시망막모세포류수술연합방료적림상효과。방법：선취2009년1월-2012년6월적100례시망막모세포류환자，재환자지정동의적전제하，분위량조，관찰조50례재술후균접수방사치료，대조조50례부급여상규수술치료。수방2년이상，통계량조환자1년、2년생존솔급복발전이솔。결과：량조술후수방24~60개월，평균수방（43.89±5.39）개월。관찰조술후1년생존솔위100%，대조조위88%，관찰조명현고우대조조，차이구유통계학의의（P<0.05）。관찰조술후1년복발전이솔위2%，대조조위18%，관찰조명현저우대조조，차이구유통계학의의（P<0.05）。관찰조술후2년생존솔위98%，대조조위80%，관찰조명현고우대조조，차이구유통계학의의（P<0.05）。관찰조술후2년복발전이솔위8%，대조조위24%，관찰조명현저우대조조，차이구유통계학의의（P<0.05）。결론：술후방료재시망막모세포류적치료중기도중요작용，가체도공제종류복발전이、제고생존솔적목적。
Objective:To investigate the clinical effect of retinoblastoma operation combined with radiotherapy in the treatment of retinoblastoma.Method:100 cases of retinoblastoma were selected from January 2009 to June 2012 , upon the patients informed consent, they were divided into two groups, 50 cases in the observation group received radiotherapy after operation, 50 patients in the control group only received routine operation therapy. They were followed up for more than 2 years , 1 years and 2 years survival rate and recurrence rate were counted between two groups.Result:Two groups were followed up for 24-60 months, mean follow-up time were (43.89±5.39) months. The 1 year survival rat of the observation group was 100%, 1 year survival rate of the control group was 88%, the observation group was significantly higher than the control group, the difference was statistically significant (P<0.05). The 1 year recurrence rate of the patients in the observation group was 2%, 1 year recurrence rate of the control group was 18% , the observation group was significantly lower than that of the control group, the difference was statistically significant (P<0.05).The 2 year survival rate of the observation group was 98%, 2 year survival rate of the control group was 80%, the observation group was significantly higher than the control group, the difference was statistically significant(P<0.05). The 2 year recurrence rate of the patients in the observation group was 8%, the 2 year recurrence rate of the control group was 24%, the observation group was significantly lower than that of the control group,the difference was statistically significant(P<0.05).Conclusion:The postoperative radiotherapy in the treatment of retinoblastoma plays an important role, which can control the tumor recurrence and metastasis, improve the survival rate .
