武汉轻工大学学报
武漢輕工大學學報
무한경공대학학보
Journal of Wuhan Polytechnic University
2014年
3期
116-120
,共5页
心率%急性心肌梗死%梗死后心绞痛%综合分析
心率%急性心肌梗死%梗死後心絞痛%綜閤分析
심솔%급성심기경사%경사후심교통%종합분석
heart rate%acute myocardial infarction%postinfarction angina pectoris%Meta analysis
采用Meta分析（ Meta analysis ）的方法确定我国人群心率对急性心肌梗死（ Acute myo-cardia infarction ，AMI）患者梗死后心绞痛发生的影响。全面收集国内发表的有关AMI患者静息心率与梗死后心绞痛关系的文献，对符合条件的所有研究结果利用RevMan软件进行固定效应模型的Meta分析。计算AMI患者心率慢组相对心率快组发生梗死后心绞痛的危险（ rel-ative risk，RR），评价心率快慢对AMI患者梗死后心绞痛发生的影响，并用漏斗图分析发表性偏倚。符合纳入标准的共7篇文献，总样本量1888例。其中心率慢组1030例，发生梗死后心绞痛128例；心率快组858例，发生梗死后心绞痛247例；合并RR＝0．46，95％可信区间是0．38-0．55。漏斗图分析提示不存在发表性偏倚。 AMI后心率增快者发生梗死后心绞痛危险增加，减慢心率可预防梗死后心绞痛的发生。
採用Meta分析（ Meta analysis ）的方法確定我國人群心率對急性心肌梗死（ Acute myo-cardia infarction ，AMI）患者梗死後心絞痛髮生的影響。全麵收集國內髮錶的有關AMI患者靜息心率與梗死後心絞痛關繫的文獻，對符閤條件的所有研究結果利用RevMan軟件進行固定效應模型的Meta分析。計算AMI患者心率慢組相對心率快組髮生梗死後心絞痛的危險（ rel-ative risk，RR），評價心率快慢對AMI患者梗死後心絞痛髮生的影響，併用漏鬥圖分析髮錶性偏倚。符閤納入標準的共7篇文獻，總樣本量1888例。其中心率慢組1030例，髮生梗死後心絞痛128例；心率快組858例，髮生梗死後心絞痛247例；閤併RR＝0．46，95％可信區間是0．38-0．55。漏鬥圖分析提示不存在髮錶性偏倚。 AMI後心率增快者髮生梗死後心絞痛危險增加，減慢心率可預防梗死後心絞痛的髮生。
채용Meta분석（ Meta analysis ）적방법학정아국인군심솔대급성심기경사（ Acute myo-cardia infarction ，AMI）환자경사후심교통발생적영향。전면수집국내발표적유관AMI환자정식심솔여경사후심교통관계적문헌，대부합조건적소유연구결과이용RevMan연건진행고정효응모형적Meta분석。계산AMI환자심솔만조상대심솔쾌조발생경사후심교통적위험（ rel-ative risk，RR），평개심솔쾌만대AMI환자경사후심교통발생적영향，병용루두도분석발표성편의。부합납입표준적공7편문헌，총양본량1888례。기중심솔만조1030례，발생경사후심교통128례；심솔쾌조858례，발생경사후심교통247례；합병RR＝0．46，95％가신구간시0．38-0．55。루두도분석제시불존재발표성편의。 AMI후심솔증쾌자발생경사후심교통위험증가，감만심솔가예방경사후심교통적발생。
By Meta analysis ,we determined the influence of heart rate on postinfarction angina pectoris incidence in Chinese population with acute myocardial infarction .A comprehensive collection of an epidemiological study pub-lished domestically on the relationship between resting heart rate and postinfarction angina pectoris in AMI patients , was carried out , for making the Meta analysis by using RevMan software with fixed effects model and random effects model.We calculated the relative risk (RR) of postinfarction angina pectoris risk of AMI patients in slow heart rate group relative to quick heart rate group ,and evaluated the influence of heart rate level with AMI on occurrence of postinfarction angina pectoris , and analyzed the publication bias by funnel plot .The 7 articles were included .The total sample size was 1888 cases.There were 1030 cases in the heart rate slow group ,and postinfarction angina pec-toris appeared in 128 cases.The heart rate quick group was 858 cases, 247 cases combined with postinfarction angi-na pectoris;RR=0 .46 ,95%confidence interval was ( 0 .38-0 .55 ) .Funnel plot analysis showed no presence of publication bias .There is a correlation between heart rate level and postinfarction angina pectoris occurrence in AMI patients .Postinfarction angina pectoris is increased in heart rate quick patients .Slowing down the heart rate may re-duce the risk of postinfarction angina pectoris .
