中国循证心血管医学杂志
中國循證心血管醫學雜誌
중국순증심혈관의학잡지
CHINESE JOURNAL OF EVIDENCE-BASES CARDIOVASCULAR MEDICINE
2014年
4期
430-431
,共2页
B型钠尿肽%心房颤动%心功能不全%预测价值
B型鈉尿肽%心房顫動%心功能不全%預測價值
B형납뇨태%심방전동%심공능불전%예측개치
B-type natriuretic peptide%Atrial fibrillation%Heart failure%Predictive value
目的：通过测定心力衰竭（心衰）患者的血清脑钠肽（BNP）浓度，探讨BNP对心衰患者并发心房颤动（房颤）的预测价值。方法入选2010年7月至2013年12月在河南省安阳地区医院心内二科住院的心衰患者169例，152例完成随访，失访17例，其中男性79例，女性73例，年龄37~71岁，平均年龄（48±11）岁，根据随访结果将患者分为两组，房颤组（n=29）和窦性心律组（n=123）。所有患者在入选前以及随访1年均行Holter检查，同时检测患者血清BNP水平。结果随访1年后，152例患者完成随访，其中有29例患者记录到房颤。房颤组[（312.21±52.78）pg/ml]BNP水平明显高于窦性心律组[（218.24±67.45）pg/ml]，差异具有统计学意义（P＜0.01）。多因素分析结果显示，年龄OR值为4.162，95％CI：1.521-7.132；LVEF OR值为1.027，95％CI：0.939-1.058。年龄和左室射血分数（LVEF）是心衰患者并发房颤的独立危险因素。结论血清BNP水平对心衰患者是否发生房颤有重要的预测价值。
目的：通過測定心力衰竭（心衰）患者的血清腦鈉肽（BNP）濃度，探討BNP對心衰患者併髮心房顫動（房顫）的預測價值。方法入選2010年7月至2013年12月在河南省安暘地區醫院心內二科住院的心衰患者169例，152例完成隨訪，失訪17例，其中男性79例，女性73例，年齡37~71歲，平均年齡（48±11）歲，根據隨訪結果將患者分為兩組，房顫組（n=29）和竇性心律組（n=123）。所有患者在入選前以及隨訪1年均行Holter檢查，同時檢測患者血清BNP水平。結果隨訪1年後，152例患者完成隨訪，其中有29例患者記錄到房顫。房顫組[（312.21±52.78）pg/ml]BNP水平明顯高于竇性心律組[（218.24±67.45）pg/ml]，差異具有統計學意義（P＜0.01）。多因素分析結果顯示，年齡OR值為4.162，95％CI：1.521-7.132；LVEF OR值為1.027，95％CI：0.939-1.058。年齡和左室射血分數（LVEF）是心衰患者併髮房顫的獨立危險因素。結論血清BNP水平對心衰患者是否髮生房顫有重要的預測價值。
목적：통과측정심력쇠갈（심쇠）환자적혈청뇌납태（BNP）농도，탐토BNP대심쇠환자병발심방전동（방전）적예측개치。방법입선2010년7월지2013년12월재하남성안양지구의원심내이과주원적심쇠환자169례，152례완성수방，실방17례，기중남성79례，녀성73례，년령37~71세，평균년령（48±11）세，근거수방결과장환자분위량조，방전조（n=29）화두성심률조（n=123）。소유환자재입선전이급수방1년균행Holter검사，동시검측환자혈청BNP수평。결과수방1년후，152례환자완성수방，기중유29례환자기록도방전。방전조[（312.21±52.78）pg/ml]BNP수평명현고우두성심률조[（218.24±67.45）pg/ml]，차이구유통계학의의（P＜0.01）。다인소분석결과현시，년령OR치위4.162，95％CI：1.521-7.132；LVEF OR치위1.027，95％CI：0.939-1.058。년령화좌실사혈분수（LVEF）시심쇠환자병발방전적독립위험인소。결론혈청BNP수평대심쇠환자시부발생방전유중요적예측개치。
Objective To investigate the predictive value of B-type natriuretic peptide (BNP) to atrial fibrillation (AF) in patients with heart failure through detecting the level of serum BNP level. Methods The patients (n=169) were chosen from Jul. 2010 to Dec. 2013 and among them, 17 were missed and 152 were followed up. There were 79 male patients and 73 female ones aged from 37 to 71, and average age was (48±11) years old. All patients were divided, according to follow-up results, into AF group (n=29) and sinus rhythm group (n=123). All patients were given Holter test before chosen and after followed up for 1 y, and at the same time BNP level was detected. Results After 1 y, 152 patients completed follow-up and AF was recorded in 29 patients. BNP level was significantly higher in AF group [(312.21±52.78) pg/mL] than that in sinus rhythm group [(218.24±67.45) pg/mL, P<0.01]. The results of multi-factor analysis showed that age (OR=4.162, 95%CI:1.521-7.132) and LVEF (OR=1.027, 95%CI:0.939-1.058) were independent risk factors of heart failure complicating AF. Conclusion The level of serum BNP is important to the prediction of AF in patients with heart failure.
