CAJ | 학술논문

目的：探讨成人肾母细胞瘤的诊断和治疗方法。方法回顾性分析12例成人肾母细胞瘤患者的临床资料。结果本组患者年龄16~63岁,表现为肉眼血尿2例,腰腹痛6例,4例为体检发现；术前诊断为肾肿瘤9例,肾盂肿瘤3例。12例均行手术治疗,术后病理均诊断为肾母细胞瘤。按照美国国家肾母细胞瘤研究组(NWTS)分期标准,本组分别为Ⅰ期5例、Ⅱ期3例、Ⅲ期3例、Ⅳ期1例。术后辅以放疗和化疗,平均随访41个月,3年生存率为48%。结论成人肾母细胞瘤是一种比较少见的恶性肿瘤,术前确诊困难,手术治疗并辅以放疗、化疗是其主要的治疗方法。
목적：탐토성인신모세포류적진단화치료방법。방법회고성분석12례성인신모세포류환자적림상자료。결과본조환자년령16~63세,표현위육안혈뇨2례,요복통6례,4례위체검발현；술전진단위신종류9례,신우종류3례。12례균행수술치료,술후병리균진단위신모세포류。안조미국국가신모세포류연구조(NWTS)분기표준,본조분별위Ⅰ기5례、Ⅱ기3례、Ⅲ기3례、Ⅳ기1례。술후보이방료화화료,평균수방41개월,3년생존솔위48%。결론성인신모세포류시일충비교소견적악성종류,술전학진곤난,수술치료병보이방료、화료시기주요적치료방법。
Objective To expore the diagnosis and treatment of adult Wilms‘tumor (AWT). Methods The clinical features of 12 cases of AWT were retrospectively studied. Results The age bracket of the study is 1 6 to 63.2 patients manifested as a pure gross hematuria,6 cases of waist and abdomen pain,4 cases‘s tumor is found by physical examination.The preoperative diagnosis of these patients was kidney neoplasm (9 cases),tumor of renal pelvis (3 cases)respectively.They were all confirmed as AWT postoperatively according to the clinical stages critical of NWTS,5 cases were diagnosed with stage Ⅰ,3 cases with stage Ⅱ,3 cases with stage Ⅲ,1 case with stage Ⅳ. All received adjuvant radiotherapy or chemotherapy postoperatively.The average follow-up time is 41 months,and three-year survival rate was 48%. Conclusions Wilms‘ tumor is a rare type of malignant tumor which was hard to diagnose preoperatively.The main treatment of this disease was surgery with radiotherapy and chemotherapy.