CAJ | 학술논문

[目的]观察天王补心汤治疗心阴不足型广泛性焦虑症(generalized anxiety disorder，GAD)的临床疗效。[方法]选取西苑医院神经内科门诊及住院部心阴不足型GAD患者63例，随机分为中药组、西药组、中西药组,每组21例，分别给予天王补心汤、帕罗西汀、天王补心汤和帕罗西汀治疗，疗程均为8周。治疗前后采用汉密尔顿焦虑量表（HAMA）进行焦虑评分，对比临床疗效。[结果]3组的总有效率没有明显差异（P＞0.05），但中西药组治疗前后HAMA下降程度明显，且治疗后评分明显低于其他两组（P＜0.05），其中中药组和中西药组的副作用低于西药组。[结论]天王补心汤治疗心阴不足型GAD能起到与帕罗西汀相同的疗效，且中西药结合治疗临床效果更显著。
[목적]관찰천왕보심탕치료심음불족형엄범성초필증(generalized anxiety disorder，GAD)적림상료효。[방법]선취서원의원신경내과문진급주원부심음불족형GAD환자63례，수궤분위중약조、서약조、중서약조,매조21례，분별급여천왕보심탕、파라서정、천왕보심탕화파라서정치료，료정균위8주。치료전후채용한밀이돈초필량표（HAMA）진행초필평분，대비림상료효。[결과]3조적총유효솔몰유명현차이（P＞0.05），단중서약조치료전후HAMA하강정도명현，차치료후평분명현저우기타량조（P＜0.05），기중중약조화중서약조적부작용저우서약조。[결론]천왕보심탕치료심음불족형GAD능기도여파라서정상동적료효，차중서약결합치료림상효과경현저。
Objective] To observe the clinical effects of Tianwang Buxin decoction in the treatment of heart Yin deficiency type of Generalized Anxiety Disorder. [Methods] 63 patients with Generalized Anxiety Disorder(heart Yin deficiency type) were randomly divided into three groups: Tianwang Buxin decoction group, paroxetine group, Tianwang Buxin decoction combined paroxetine group, course of treatment for 8weeks.Contrast the scores of three groups by HAMA before and after treatment. [Results] The clinical efficacy was almost the same among the three groups without significant difference, but the decrease of HAMA scores of Tianwang Buxin decoction combined paroxetine group was obviously lower than Tianwang Buxin decoction group and paroxetine group(P<0.05), among which, TCM group and combination group of TCM and WM had less side effect than WM group. [Conclusion]The clinical efficacy of Tianwang Buxin decoction group is almost the same with the paroxetine group without significant difference. The clinical efficacy of Tianwang Buxin decoction combined paroxetine group is more significant.