海峡药学
海峽藥學
해협약학
STRAIT PHARMACEUTICAL JOURNAL
2014年
8期
28-30
,共3页
梁永枢%黄颖喻%罗志雄%刘军民
樑永樞%黃穎喻%囉誌雄%劉軍民
량영추%황영유%라지웅%류군민
天然牛黄%鉴别%含量测定%胆酸%胆红素
天然牛黃%鑒彆%含量測定%膽痠%膽紅素
천연우황%감별%함량측정%담산%담홍소
Natural Bovis Calculus%Quality analysis%Content determination%CA%Bilirubin
目的：对2批土耳其产牛黄与国产牛黄的质量进行分析比较，判断其是否符合我国牛黄用药标准。方法薄层色谱检识牛黄中的胆酸及胆红素；采用UV比色法测定胆红素的含量；采用薄层色谱扫描法测定胆酸的含量。结果2批牛黄中含胆红素与胆酸，土耳其产牛黄胆红素与胆酸含量分别为51.32％、4.63％，均高于现行版中国药典的标准；国产牛黄胆红素与胆酸的含量为51.56％、3.22％，其中胆酸含量达不到药典中的要求。结论该批土耳产牛黄可供药用，国产达不到入药标准。
目的：對2批土耳其產牛黃與國產牛黃的質量進行分析比較，判斷其是否符閤我國牛黃用藥標準。方法薄層色譜檢識牛黃中的膽痠及膽紅素；採用UV比色法測定膽紅素的含量；採用薄層色譜掃描法測定膽痠的含量。結果2批牛黃中含膽紅素與膽痠，土耳其產牛黃膽紅素與膽痠含量分彆為51.32％、4.63％，均高于現行版中國藥典的標準；國產牛黃膽紅素與膽痠的含量為51.56％、3.22％，其中膽痠含量達不到藥典中的要求。結論該批土耳產牛黃可供藥用，國產達不到入藥標準。
목적：대2비토이기산우황여국산우황적질량진행분석비교，판단기시부부합아국우황용약표준。방법박층색보검식우황중적담산급담홍소；채용UV비색법측정담홍소적함량；채용박층색보소묘법측정담산적함량。결과2비우황중함담홍소여담산，토이기산우황담홍소여담산함량분별위51.32％、4.63％，균고우현행판중국약전적표준；국산우황담홍소여담산적함량위51.56％、3.22％，기중담산함량체불도약전중적요구。결론해비토이산우황가공약용，국산체불도입약표준。
OBJECTIVE To analyse the quality of natural Bovis Calculus from Turkey and China.METHODS TLC was used to identificate cholic acid ( CA) and bilirubin in Bovis Calculus.Bilirubin content was determined by UV colorimetric method.Cholic acid content was determined by TLC scanning method.RESULTS The contents of CA and bilirubin in the Turkish sample were 51.32%and 4.63%,and were higher than the standard of Pharmaco-poeia of People′s Republic of China respectively.The contents of CA and bilirubin in the domestic sample were 3.22%and 51.56% respectively.CONCLUSION Calculus Bovis from turkey can be used for medicinal prod-ucts.
