CAJ | 학술논문

目的：探讨高钠血症在神经重症患者中的发生率，及其对住院患者病死率、住院时间和住院费用的影响。方法回顾性分析2011年1～12月本院收治的神经IC U重症患者274例，死亡52例，存活222例。将血清钠＞150 mmol/L定义为高钠血症，并进行统计学分析。结果死亡患者中高钠血症26例，存活患者23例，两者比较差异有统计学意义（50．0％ vs 10．4％，P＝0．000）。高钠血症是神经重症患者死亡的独立风险因素（OR＝5．08，95％ C I：2．21～11．63，P＝0．000）。高钠血症患者与住院费用呈正相关，但差异无统计学意义（β＝0．023，P＝0.756）；高钠血症患者与住院天数呈正相关，差异无统计学意义（β＝0．094，P＝0．200）。结论高钠血症在神经重症患者中具有更高的发生率，而且是神经重症患者死亡的独立风险因素，且与患者住院时间与住院费用呈正相关。
목적：탐토고납혈증재신경중증환자중적발생솔，급기대주원환자병사솔、주원시간화주원비용적영향。방법회고성분석2011년1～12월본원수치적신경IC U중증환자274례，사망52례，존활222례。장혈청납＞150 mmol/L정의위고납혈증，병진행통계학분석。결과사망환자중고납혈증26례，존활환자23례，량자비교차이유통계학의의（50．0％ vs 10．4％，P＝0．000）。고납혈증시신경중증환자사망적독립풍험인소（OR＝5．08，95％ C I：2．21～11．63，P＝0．000）。고납혈증환자여주원비용정정상관，단차이무통계학의의（β＝0．023，P＝0.756）；고납혈증환자여주원천수정정상관，차이무통계학의의（β＝0．094，P＝0．200）。결론고납혈증재신경중증환자중구유경고적발생솔，이차시신경중증환자사망적독립풍험인소，차여환자주원시간여주원비용정정상관。
Objective To study the incidence of hypernatremia and its effect on mortality ,hospital stay time and cost in neurocrtically ill patients .Methods The clinical data about 274 neurocriti-cally ill patients (52 died ,222 survived) admitted to our department were retrospectively ana-lyzed .Hypernatremia was diagnosed when the serum sodium level was >150 mmol/L .Results Of the 52 died patients and the 222 survived patients ,26 (50 .0% ) and 23 (10 .4% ) were diagnosed with hypernatremia respectively (P=0 .000) .Hypernatremia was an independent risk factor for the death of neurocritically ill patients (OR=5 .08 ,95% CI:2 .21-11 .63 ,P=0 .000)and was pos-itively related with their hospital stay time (days)and cost although no significant difference was found between them (β=0 .023 ,P=0 .756 ;β=0 .094 ,P=0 .200) .Conclusion The incidence of hypernatremia is high in neurocritically ill patients .Hypernatremia is an independent risk factor for their death and positively related with their hospital stay time and cost .