CAJ | 학술논문

目的：探讨197例脑梗死合并2型糖尿病患者的颅内外动脉粥样硬化性狭窄的特征。方法回顾性分析南京卒中注册系统中提取2007年3月～2011年3月经数字减影血管造影术证实的脑梗死合并糖尿病患者的人口统计学特征与脑动脉粥样硬化性狭窄的分布、程度、类型及病变血管段部位等。结果197例糖尿病合并脑梗死患者中，男性明显多于女性（68％vs32％），发病年龄男性小于女性[（61．32±10．93）vs（67．27±10．14），P＜0．05）]；脑血管病变分布前循环明显多于后循环（73．2％vs26．8％，P＜0．001）；颅内血管闭塞的发生率显著高于颅外血管（65．3％vs34．7％，P＜0．05）；最常见的受累血管为大脑前动脉与颈内动脉颅外段；前后循环的颅内血管闭塞的分布比较差异有统计学意义（P＝0．013），后循环颅内段更易发生闭塞。结论脑梗死合并2型糖尿病患者脑动脉粥样硬化性狭窄具有一定的分布特征。
목적：탐토197례뇌경사합병2형당뇨병환자적로내외동맥죽양경화성협착적특정。방법회고성분석남경졸중주책계통중제취2007년3월～2011년3월경수자감영혈관조영술증실적뇌경사합병당뇨병환자적인구통계학특정여뇌동맥죽양경화성협착적분포、정도、류형급병변혈관단부위등。결과197례당뇨병합병뇌경사환자중，남성명현다우녀성（68％vs32％），발병년령남성소우녀성[（61．32±10．93）vs（67．27±10．14），P＜0．05）]；뇌혈관병변분포전순배명현다우후순배（73．2％vs26．8％，P＜0．001）；로내혈관폐새적발생솔현저고우로외혈관（65．3％vs34．7％，P＜0．05）；최상견적수루혈관위대뇌전동맥여경내동맥로외단；전후순배적로내혈관폐새적분포비교차이유통계학의의（P＝0．013），후순배로내단경역발생폐새。결론뇌경사합병2형당뇨병환자뇌동맥죽양경화성협착구유일정적분포특정。
Objective To study the features of internal and external carotid atherosclerotic stenosis in 197 ischemic stroke patients with type 2 diabetes mellitus (DM ) .Methods Clinical data about ischemic stroke patients with type 2 DM in Nanjing Stroke Registry Program were retrospectively analyzed (demographic features ,and distribution ,severity ,types and involed vascular segments of cerebral atherosclerotic stenosis) .Results The percentage of males was higher than that of fe-males and the disease onset age was younger in males than in females in the 197 ischemic stroke patients with type 2 DM (68% vs 32% ,61 .32 ± 10 .93 years vs 67 .27 ± 10 .14 years ,P<0.05) . The distribution rate of cerebrovascular lesions was significantly higher in anterior circulation than in posterior circulation (73 .2% vs 26 .8% ,P<0 .001) .The incidence of intracranial vascular occlusion was significantly higher than that of extracranial vascular occlusion (65 .3% vs 34.7% , P<0 .05) .The commonly involved blood vessels were the anterior cerebral artery and internal ca-rotid artery .T he distribution of intracranial vascular occlusion in anterior and posterior circulation differed greatly (P=0 .013) .Conclusion The distribution of cerebral atherosclerotic stenosis is of certain characteristics in ischemic stroke patients with type 2 DM .