CAJ | 학술논문

胃肠道间质瘤（GIST）是胃肠道及腹腔最常见的间叶源性肿瘤，对常规的放疗、化疗均不敏感。外科手术是局限性GIST患者的主要治疗方式，但术后复发率较高。对于术前、术后辅助、复发、转移及不能手术切除的患者，酪氨酸激酶抑制剂甲磺酸伊马替尼对其有较好的治疗效果。本文对甲磺酸伊马替尼治疗胃肠道间质瘤的研究进展作一综述。
위장도간질류（GIST）시위장도급복강최상견적간협원성종류，대상규적방료、화료균불민감。외과수술시국한성GIST환자적주요치료방식，단술후복발솔교고。대우술전、술후보조、복발、전이급불능수술절제적환자，락안산격매억제제갑광산이마체니대기유교호적치료효과。본문대갑광산이마체니치료위장도간질류적연구진전작일종술。
Gastrointestinal stromal tumor(GIST)is the most common mesenchymal malignancy of the gastrointestinal tract and abdominal cavity.It is unresponsive to standard chemotherapy and to radiotherapy.The main treatment is surgery for limitations of GIST patients,but the postoperative recurrence rate of GIST patients is higher,for preopera-tive,postoperative adjuvant,recurrence,metastasis and not surgical resection of the GIST patients.Tyrosine kinase in-hibitor imatinib mesylate has good effect.This article will review the research progress of imatinib mesylate on gastro-intestinal stromal tumor.