CAJ | 학술논문

目的：探讨MRI与CT成像差异对鼻咽癌（NPC）侵犯范围的界定及三维适形放疗靶区勾画的影响。方法：我院经病理证实的初诊NPC患者85例行CT与MRI检查，对比其向周围结构侵犯和淋巴结转移的异同。分别勾画鼻咽原发肿瘤范围并比较其靶体积（GTV）的差异。结果：MRI和CT显示椎前肌侵犯、颅底骨质破坏、咽后淋巴结转移分别为44、59、56例和65、28、23例，差异具有统计学意义（P＜0．01）。GTV-MRI较GTV-CT平均增大35．67％，差异具有统计学意义（P＜0．01）。结论：MRI对NPC侵犯范围的显示较CT有优势，联合应用将有助于提高NPC放疗靶区勾画的精确性，减少肿瘤靶区的遗漏。
목적：탐토MRI여CT성상차이대비인암（NPC）침범범위적계정급삼유괄형방료파구구화적영향。방법：아원경병리증실적초진NPC환자85례행CT여MRI검사，대비기향주위결구침범화림파결전이적이동。분별구화비인원발종류범위병비교기파체적（GTV）적차이。결과：MRI화CT현시추전기침범、로저골질파배、인후림파결전이분별위44、59、56례화65、28、23례，차이구유통계학의의（P＜0．01）。GTV-MRI교GTV-CT평균증대35．67％，차이구유통계학의의（P＜0．01）。결론：MRI대NPC침범범위적현시교CT유우세，연합응용장유조우제고NPC방료파구구화적정학성，감소종류파구적유루。
Objective:To investigate the impact of difference between MRI and CT finding on involved structures of nasopharynx and gross target volume (GTV)of the three-dimensional conformal radiotherapy (3DCRT)in naso-pharyngeal carcinoma (NPC).Methods:All 85 cases of NPC confirmed by pathology were performed CT and MRI scanning before treatment,the similarities and differences of involving structure of nasopharynx and lymph node metas-tasis showed on MRI and CT were compared,GTV based MRI and CT were delineated respectively and the volumes were compared.Results:Prevertebral muscle invasion,skull base invasion and retropharyngeal lymph node metastasis shown on MRI and CT were 44,59,56 cases and 65,28,23 cases respectively,the difference was statistically signifi-cant (P<0.01).GTV-MRI increased by 35.67%on an average,compared with GTV-CT,the difference was sta-tistically significant (P<0.01).Conclusion:MRI is superior to CT in demonstrating the involved structures of naso-pharynx for NPC,and combined application of both can improve the contouring of target volume and minimize the missing of tumor target.