CAJ | 학술논문

目的：探讨消糜阴道泡腾片对大鼠细菌阴道炎模型的治疗作用。方法将雌性大鼠随机分为正常对照组、模型组、消糜阴道泡腾片治疗组、氧氟沙星栓剂对照组。除正常对照组外，其余各组大鼠建立细菌性阴道炎模型，成模后给药，末次药后取阴道分泌物涂片染色镜检验；处死大鼠，取阴道组织，进行病理学的检查。结果消糜阴道泡腾片高剂量抗大鼠细菌性阴道炎的总有效率为91.7%，与氧氟沙星栓组比较无统计学意义（P ﹥0.05）。结论消糜阴道泡腾片对大鼠细菌性阴道炎具有显著的治疗作用。
목적：탐토소미음도포등편대대서세균음도염모형적치료작용。방법장자성대서수궤분위정상대조조、모형조、소미음도포등편치료조、양불사성전제대조조。제정상대조조외，기여각조대서건립세균성음도염모형，성모후급약，말차약후취음도분비물도편염색경검험；처사대서，취음도조직，진행병이학적검사。결과소미음도포등편고제량항대서세균성음도염적총유효솔위91.7%，여양불사성전조비교무통계학의의（P ﹥0.05）。결론소미음도포등편대대서세균성음도염구유현저적치료작용。
Objective To investigate the therapeutic effects of Xiaomi Vagina Effervescent Tablets on bacteria vaginitis model in rats. Methods Female rats were randomly divided into normal control group,model group,Xiaomi Vagina Effer-vescent Tablets treatment group,Ofloxacin Suppositories control group. Except normal control group,establishment of bacte-rial vaginitis model in the remaining rats,into the mold after the administration,after last administration,vaginal secretion smear staining microscopic examination;The rats were sacrificed,and vaginal tissue was took to carry out pathologic exami-nation. Results The high dose of Xiaomi Vagina Effervescent Tablets in rats with bacterial vaginosis total efficiency was 91. 7% ,there was no statistical significance compared with the Ofloxacin Suppositories group(P ﹥ 0. 05). Conclusion Xiaomi Vagina Effervescent Tablets in the treatment of bacterial vaginosis rats had significantly therapeutic effect.