CAJ | 학술논문

目的：分析术前行新辅助放化疗联合手术治疗FIGO Ib2~Ⅱb期宫颈癌患者的临床疗效。方法：对手术治疗的40例宫颈癌患者,术前行新辅助化疗1次,对于子宫颈病灶>4 cm,术前大出血者加腔内后装治疗1次。3周后行宫颈癌根治术。通过分析患者瘤体大小的改变、放化疗不良反应、手术难度的下降及术后病理改变等结果,评价新辅助放化疗在宫颈癌治疗中的安全性。结果：宫颈癌新辅助放化疗总有效率为82.5%,手术切除成功率为100%。结论：术前新辅助放化疗联合手术治疗宫颈癌Ib2~Ⅱb期患者安全有效,可提高手术的治疗效果,降低并发症发生率。
목적：분석술전행신보조방화료연합수술치료FIGO Ib2~Ⅱb기궁경암환자적림상료효。방법：대수술치료적40례궁경암환자,술전행신보조화료1차,대우자궁경병조>4 cm,술전대출혈자가강내후장치료1차。3주후행궁경암근치술。통과분석환자류체대소적개변、방화료불량반응、수술난도적하강급술후병리개변등결과,평개신보조방화료재궁경암치료중적안전성。결과：궁경암신보조방화료총유효솔위82.5%,수술절제성공솔위100%。결론：술전신보조방화료연합수술치료궁경암Ib2~Ⅱb기환자안전유효,가제고수술적치료효과,강저병발증발생솔。
Objective:To explore the clinical efficiency of the preoperative neoadjuvant chemotherapy and radiotherapy combined with operation in the treatment of FIGO Ib-Ⅱb stage cervical carcinoma. Methods:Forty operation patients were treated with preoperative neoadjuvant chemotherapy and radiotherapy. the radical resections in the patients with cervical lesions more than 4 cm. preoperative massive hemorrhage treated with intracavitary brachytherapy after 3 weeks were implemented. The safety of neoadjuvant chemotherapy and radiotherapy was evaluated by the tumor size change,adverse reaction of chemotherapy and radiotherapy,operation difficulty change and postoperative pathological change. Results:The total effective rate and success rate of operation in the cervical carcinoma patients treated with neoadjuvant chemotherapy and radiotherapy were 82. 5% and 100%, respectively. Conclusions:The neoadjuvant chemotherapy and radiotherapy combined with operation in treating the Ib2-Ⅱb stage cervical carcinoma is safe and effective. which can improve the operative effects and decrease the incidence of complications.