CAJ | 학술논문

目的：比较18 F-FDG PET/CT与增强CT在肺癌淋巴结术前诊断及分期中的价值。方法以病理结果为金标准,比较82例肺癌患者术前PET/CT及增强CT检查者对区域淋巴结诊断及分期的效能。结果82例患者共切除区域淋巴结564枚,其中78枚(13.8%)证实为转移。 PET/CT诊断区域淋巴结转移的灵敏度、特异度、准确度、阳性预测值及阴性预测值均显著高于增强CT,P均<0.05。 PET/CT与增强CT对区域淋巴结分期总的准确性分别为[87.8%(72/82)及70.7%(50/82)],P<0.05；对区域淋巴结N0、N1、N2期诊断的准确性分别为[89.3%(25/28)、83.3%(20/24)、90.0%(27/30)] vs [85.7%(24/28)、50.0%(12/24)、73.3%(22/30)]。结论 PET/CT诊断区域淋巴结转移的效能高于增强CT,但是仍存在一定的假阳性及假阴性。临床工作中需要结合患者的临床资料,进一步提高诊断及分期的准确性。
목적：비교18 F-FDG PET/CT여증강CT재폐암림파결술전진단급분기중적개치。방법이병리결과위금표준,비교82례폐암환자술전PET/CT급증강CT검사자대구역림파결진단급분기적효능。결과82례환자공절제구역림파결564매,기중78매(13.8%)증실위전이。 PET/CT진단구역림파결전이적령민도、특이도、준학도、양성예측치급음성예측치균현저고우증강CT,P균<0.05。 PET/CT여증강CT대구역림파결분기총적준학성분별위[87.8%(72/82)급70.7%(50/82)],P<0.05；대구역림파결N0、N1、N2기진단적준학성분별위[89.3%(25/28)、83.3%(20/24)、90.0%(27/30)] vs [85.7%(24/28)、50.0%(12/24)、73.3%(22/30)]。결론 PET/CT진단구역림파결전이적효능고우증강CT,단시잉존재일정적가양성급가음성。림상공작중수요결합환자적림상자료,진일보제고진단급분기적준학성。
Objective To compare the efficiency of 18 F-FDG PET/CT and CECT in lymph node staging for patients with lung cancer. Methods 82 patients with lung cancer underwent both PET/CT and chest CECT examina-tion. With pathologic results as the gold standard, the efficiency in diagnosing and staging regional lymph nodes was compared. Results A total of 564 mediastinal lymph nodes were resected in 82 patients and 13. 8% were confirmed as metastases by pathology. PET/CT was superior to CECT in diagnosing regional lymph node (P<0. 05). The ac-curacy of PET/CT and CECT in staging N0, N1, N2 was [89. 3% (25/28), 83. 3% (20/24), 90. 0% (27/30)] VS [85. 7% (24/28), 50. 0% (12/24), 73. 3% (22/30)]. Consistency of PET/CT and CECT in lymph node staging with pathological was respectively 87. 8% (72/82) vs 70. 7% (50/82) (P<0. 05). Conclusion 18F-FDG PET/CT is more accurate for evaluating metastatic lymph nodes and staging in patients with lung cancer than CECT. In our clinical work, integrated application of 18 F-FDG PET/CT and clinical data is needed.