临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2014年
10期
1816-1818,1819
,共4页
肺部感染%病原菌%抗菌药物
肺部感染%病原菌%抗菌藥物
폐부감염%병원균%항균약물
lung infection%pathogens%antimicrobial drugs
目的：探讨引起肺部感染的病原菌及其耐药状况。方法对187例肺部感染患者痰液标本进行病原菌鉴定及药敏试验检测，分析结果。结果187份标本共检出病原菌164株，培养阳性率为87.70%，其中革兰氏阴性菌占71.95%，革兰氏阳性菌占18.29%，真菌占9.76%，革兰阴性菌中以铜绿假单胞菌、肺炎克雷伯菌、大肠埃希氏菌、肠杆菌属、鲍曼不动杆菌为主，革兰氏阳性菌中以金黄色葡萄球菌、肺炎链球菌、溶血性葡萄球菌为主，真菌主要为白色假丝酵母菌，占7.93%；检出的革兰氏阴性菌对亚胺培南、美罗培南、阿米卡星耐药率低，铜绿假单胞菌对氨苄西林、氨苄西林/舒巴坦完全耐药，肺炎克雷伯菌对氨苄西林完全耐药，肠杆菌属对头孢呋辛酯完全耐药，鲍曼不动杆菌对氨曲南、头孢呋辛酯完全耐药；检出的革兰氏阳性菌对万古霉素、夫西地酸、莫西沙星耐药率低，金黄色葡萄球菌对红霉素、克林霉素完全耐药，肺炎链球菌对红霉素完全耐药，溶血性葡萄球菌对青霉素、氨苄西林、氨苄西林/舒巴坦、亚胺培南、红霉素、克林霉素、环丙沙星、庆大霉素、磷霉素均完全耐药。结论引起肺部感染患者的病原菌主要以铜绿假单胞菌、肺炎克雷伯菌、大肠埃希氏菌、肠杆菌属、鲍曼不动杆菌为主的革兰氏阴性菌为主，检出病原菌均对临床常用抗菌药物存在一定耐药性。
目的：探討引起肺部感染的病原菌及其耐藥狀況。方法對187例肺部感染患者痰液標本進行病原菌鑒定及藥敏試驗檢測，分析結果。結果187份標本共檢齣病原菌164株，培養暘性率為87.70%，其中革蘭氏陰性菌佔71.95%，革蘭氏暘性菌佔18.29%，真菌佔9.76%，革蘭陰性菌中以銅綠假單胞菌、肺炎剋雷伯菌、大腸埃希氏菌、腸桿菌屬、鮑曼不動桿菌為主，革蘭氏暘性菌中以金黃色葡萄毬菌、肺炎鏈毬菌、溶血性葡萄毬菌為主，真菌主要為白色假絲酵母菌，佔7.93%；檢齣的革蘭氏陰性菌對亞胺培南、美囉培南、阿米卡星耐藥率低，銅綠假單胞菌對氨芐西林、氨芐西林/舒巴坦完全耐藥，肺炎剋雷伯菌對氨芐西林完全耐藥，腸桿菌屬對頭孢呋辛酯完全耐藥，鮑曼不動桿菌對氨麯南、頭孢呋辛酯完全耐藥；檢齣的革蘭氏暘性菌對萬古黴素、伕西地痠、莫西沙星耐藥率低，金黃色葡萄毬菌對紅黴素、剋林黴素完全耐藥，肺炎鏈毬菌對紅黴素完全耐藥，溶血性葡萄毬菌對青黴素、氨芐西林、氨芐西林/舒巴坦、亞胺培南、紅黴素、剋林黴素、環丙沙星、慶大黴素、燐黴素均完全耐藥。結論引起肺部感染患者的病原菌主要以銅綠假單胞菌、肺炎剋雷伯菌、大腸埃希氏菌、腸桿菌屬、鮑曼不動桿菌為主的革蘭氏陰性菌為主，檢齣病原菌均對臨床常用抗菌藥物存在一定耐藥性。
목적：탐토인기폐부감염적병원균급기내약상황。방법대187례폐부감염환자담액표본진행병원균감정급약민시험검측，분석결과。결과187빈표본공검출병원균164주，배양양성솔위87.70%，기중혁란씨음성균점71.95%，혁란씨양성균점18.29%，진균점9.76%，혁란음성균중이동록가단포균、폐염극뢰백균、대장애희씨균、장간균속、포만불동간균위주，혁란씨양성균중이금황색포도구균、폐염련구균、용혈성포도구균위주，진균주요위백색가사효모균，점7.93%；검출적혁란씨음성균대아알배남、미라배남、아미잡성내약솔저，동록가단포균대안변서림、안변서림/서파탄완전내약，폐염극뢰백균대안변서림완전내약，장간균속대두포부신지완전내약，포만불동간균대안곡남、두포부신지완전내약；검출적혁란씨양성균대만고매소、부서지산、막서사성내약솔저，금황색포도구균대홍매소、극림매소완전내약，폐염련구균대홍매소완전내약，용혈성포도구균대청매소、안변서림、안변서림/서파탄、아알배남、홍매소、극림매소、배병사성、경대매소、린매소균완전내약。결론인기폐부감염환자적병원균주요이동록가단포균、폐염극뢰백균、대장애희씨균、장간균속、포만불동간균위주적혁란씨음성균위주，검출병원균균대림상상용항균약물존재일정내약성。
Objective To investigate the cause of lung infection pathogens and drug resistance. Methods The sputum specimens of 187 cases of lung infection were collected for pathogen identification and susceptibility test. Results 164 strains of pathogens were detected, and the culture positive rate was 87. 70%, which included Gram-negative bacteria (71. 95%), Gram-positive bacteria (18. 29%), fungi (9. 76%). Gram-negative bacteria mainly included pseudomonas aeruginosa aeromonas, klebsiella pneumoniae, escherichia coli, enterobacter and acinetobacter baumannii. Gram-positive bacteria mainly included staphylococcus aureus, streptococcus pneumoniae and hemolytic staphylococci. Fungi mainly included candida albicans. Gram-negative bacteria showed a low resistance to imipenem, meropenem and amikacin. Pseudomonas aeruginosa showed a complete resistance to ampicillin and ampicillin/sulbac-tam. Klebsiella pneumoniae was completely resistant to ampicillin, and enterobacter complete resistant to cefuroxime axetil. Acinetobacter baumannii showed a complete resistance to aztreonam and cefuroxime axetil. Gram -positive bacteria showed a low resistance to vancomycin, fusidic acid and moxifloxacin. Staphylococcus aureus was totally re-sistant to erythromycin and clindamycin, and streptococcus pneumoniae to erythromycin. Hemolytic staphylococci was fully resistant to penicillin, ampicillin, ampicillin/sulbactam, imipenem, erythromycin, clindamycin, ciprofloxacin, gentamicin and fosfomycin. Conclusion The cause pathogens of lung infection mainly include pseudomonas aerugi-nosa, klebsiella pneumoniae, escherichia coli, enterobacter and acinetobacter baumannii, which all show a certain resistance to many commonly used antibiotics.
