临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2014年
10期
1764-1766,1767
,共4页
支气管哮喘%过敏性鼻炎%呼出气一氧化氮%外周血嗜酸粒细胞%受试者工作曲线
支氣管哮喘%過敏性鼻炎%呼齣氣一氧化氮%外週血嗜痠粒細胞%受試者工作麯線
지기관효천%과민성비염%호출기일양화담%외주혈기산립세포%수시자공작곡선
bronchial asthma%allergic rhinitis%fractional exhaled nitric oxide%peripheral blood eosinophilia granulocyte classification%receiver operating characteristic curves
目的：探讨呼出气一氧化氮( Fe NO)在支气管哮喘( BA )和过敏性鼻炎( AR)患者中的应用,比较Fe NO和外周血嗜酸粒细胞分类( EOS%)在健康对照组( A组)、AR( B组)、BA/AR( C组)及BA( D组)之间的不同,寻找两种疾病Fe NO、EOS%改变的意义,以及两种疾病之间的关系。方法采用按国际技术标准设计的尚沃纳库仑一氧化氮分析仪对A、B、C、D组患者检测Fe NO,同时测定各组患者血常规。结果三组病例 ROC 曲线下面积均大于0.5；AR、BA/ AR、BA 三组 Fe NO、 EOS%水平均高于对照组( P <0.05),三组组间无明显差异(P>0.05)；Fe NO与EOS%间存在显著相关性(r=0.505,P<0.05)。结论Fe NO诊断支气管哮喘和过敏性鼻炎有临床意义。 Fe NO可以反映患者气道嗜酸性炎症水平。过敏性鼻炎与支气管哮喘这两种疾病存在密切的关系。
目的：探討呼齣氣一氧化氮( Fe NO)在支氣管哮喘( BA )和過敏性鼻炎( AR)患者中的應用,比較Fe NO和外週血嗜痠粒細胞分類( EOS%)在健康對照組( A組)、AR( B組)、BA/AR( C組)及BA( D組)之間的不同,尋找兩種疾病Fe NO、EOS%改變的意義,以及兩種疾病之間的關繫。方法採用按國際技術標準設計的尚沃納庫崙一氧化氮分析儀對A、B、C、D組患者檢測Fe NO,同時測定各組患者血常規。結果三組病例 ROC 麯線下麵積均大于0.5；AR、BA/ AR、BA 三組 Fe NO、 EOS%水平均高于對照組( P <0.05),三組組間無明顯差異(P>0.05)；Fe NO與EOS%間存在顯著相關性(r=0.505,P<0.05)。結論Fe NO診斷支氣管哮喘和過敏性鼻炎有臨床意義。 Fe NO可以反映患者氣道嗜痠性炎癥水平。過敏性鼻炎與支氣管哮喘這兩種疾病存在密切的關繫。
목적：탐토호출기일양화담( Fe NO)재지기관효천( BA )화과민성비염( AR)환자중적응용,비교Fe NO화외주혈기산립세포분류( EOS%)재건강대조조( A조)、AR( B조)、BA/AR( C조)급BA( D조)지간적불동,심조량충질병Fe NO、EOS%개변적의의,이급량충질병지간적관계。방법채용안국제기술표준설계적상옥납고륜일양화담분석의대A、B、C、D조환자검측Fe NO,동시측정각조환자혈상규。결과삼조병례 ROC 곡선하면적균대우0.5；AR、BA/ AR、BA 삼조 Fe NO、 EOS%수평균고우대조조( P <0.05),삼조조간무명현차이(P>0.05)；Fe NO여EOS%간존재현저상관성(r=0.505,P<0.05)。결론Fe NO진단지기관효천화과민성비염유림상의의。 Fe NO가이반영환자기도기산성염증수평。과민성비염여지기관효천저량충질병존재밀절적관계。
Objective To discuss the application of exhaled nitric oxide ( FeNO) on patients with bronchial asthma ( BA) and allergic rhinitis ( AR) , and to investigate the significance and relationship in FeNO and EOS%between allergic rhinitis and bronchial asthma. Methods FeNO was measured by Sunvou nitric oxide analyzer ac-cording to the international standard design. FeNO test and blood routine examination were performed in all of the en-rolled patients. Results The area under ROC curve was greater than 0. 5. Compare to the normal control group, Fe-NO concentration in patients with AR, BA/AR and BA showed higher than those in the control group with significant difference (P<0. 05). There was significant correlation between FeNO concentration and EOS% in patients (r=0. 505, P<0. 05). There was no significant difference in FeNO concentration among the patients who were suffering from BA, BA/AR, AR ( P >0. 05 ) . Conclusion FeNO have clinical significance in the diagnosis of bronchial asthma and allergic rhinitis. There is a close relationship between allergic rhinitis and bronchial asthma.
