CAJ | 학술논문

目的：探讨微波消融技术对羊胸腺组织的影响。方法利用微波消融治疗仪和发射段长5 mm、直径2 mm 的电极，分别以不同功率和时间对离体羊胸腺组织进行超声引导下消融，测量气化范围及消融灶大小，并进行病理学检查。分析消融灶大小与消融功率、时间的关系；观察微波消融后羊胸腺组织的病理变化，以及超声下气化范围和实际热损伤范围的大小关系。结果随着消融时间和功率的增加，气化区长径、短径和气化范围及消融灶长径、短径和消融灶面积均呈现增大趋势；同一消融功率、时间下，气化范围小于消融灶面积（ P ﹤0.05）；消融灶质地变硬，边界清晰，光学显微镜下，消融灶内胸腺组织形态失常，其内淋巴细胞难以辨认。结论微波消融功率、时间越大，超声气化范围和消融灶大小往往越大；微波消融羊胸腺组织的热损伤范围大于超声观察的气化范围，临床通过气化范围评估消融范围并不可靠。
목적：탐토미파소융기술대양흉선조직적영향。방법이용미파소융치료의화발사단장5 mm、직경2 mm 적전겁，분별이불동공솔화시간대리체양흉선조직진행초성인도하소융，측량기화범위급소융조대소，병진행병이학검사。분석소융조대소여소융공솔、시간적관계；관찰미파소융후양흉선조직적병리변화，이급초성하기화범위화실제열손상범위적대소관계。결과수착소융시간화공솔적증가，기화구장경、단경화기화범위급소융조장경、단경화소융조면적균정현증대추세；동일소융공솔、시간하，기화범위소우소융조면적（ P ﹤0.05）；소융조질지변경，변계청석，광학현미경하，소융조내흉선조직형태실상，기내림파세포난이변인。결론미파소융공솔、시간월대，초성기화범위화소융조대소왕왕월대；미파소융양흉선조직적열손상범위대우초성관찰적기화범위，림상통과기화범위평고소융범위병불가고。
Objective To explore the size of the ovine thymus gland ablation lesions corresponding to the power and the time and the pathological change after microwave ablation,and to find the relationship of the size of gasification and lesion areas. Methods The ovine thymus gland ablation lesions were made by means of ultrasound - guided microwave ablation and the monopolar electrode with the emissive tip diameter of 2mm and tip length of 5mm in several combinations of power and time. The size of the gasification and lesion areas was measured and its pathology was studied. Results The longer diameter,shorter diameter and size of gasification and lesion areas were commonly relevant to the power and time of microwave ablation. At the same power and time,the size of gasification area was smaller than that of lesion area( P ﹤ 0. 05). The thymus gland became harder,off white in color and with well - defined border after ablation. Lymphoid cell disorder in the lesions was showed with histo-logical methods under light microscopy. Conclusion With higher power and longer time,the size of gasification and lesions tend to be bigger. The size of gasification area was smaller than that of lesion area. This method is not reliable to evaluate the area of ablation by gasification region.