CAJ | 학술논문

目的：探讨心肺复苏术后患者血清细胞间黏附分子-1(ICAM-1)的变化及临床意义。方法将病人分为心跳骤停5min内心肺复苏术组、5~10min内心肺复苏术组、10~30min内心肺复苏术组，并以健康体检人员作为对照组，共计4组，用ELISA法测各组静脉血中的ICAM-1水平。结果心肺复苏术后患者血清细胞间黏附分子-1水平均高于健康对照组(P<0.05)；且时间越长的心肺复苏术患者静脉血清细胞间黏附分子-1水平越高(P<0.05)。结论心肺复苏患者血清细胞间黏附分子-1水平会明显升高，心肺复苏术越早实施，其ICAM-1水平越低，预后越好(P<0.05)。
목적：탐토심폐복소술후환자혈청세포간점부분자-1(ICAM-1)적변화급림상의의。방법장병인분위심도취정5min내심폐복소술조、5~10min내심폐복소술조、10~30min내심폐복소술조，병이건강체검인원작위대조조，공계4조，용ELISA법측각조정맥혈중적ICAM-1수평。결과심폐복소술후환자혈청세포간점부분자-1수평균고우건강대조조(P<0.05)；차시간월장적심폐복소술환자정맥혈청세포간점부분자-1수평월고(P<0.05)。결론심폐복소환자혈청세포간점부분자-1수평회명현승고，심폐복소술월조실시，기ICAM-1수평월저，예후월호(P<0.05)。
Objective To investigate the after cardiopulmonary resuscitation in patients with serum cell adhesion molecule -1 (ICAM-1) changes and the clinical significance. Methods The patients were divided into cardiac arrest cardiopulmonary resuscitation was 5 minutes, 5-10 minutes inner CPR group, 10-30 minutes inner CPR group, and in healthy people as control group, a total of 4 groups, in each group were measured in venous blood ICAM-1 level by ELISA method. Results The level of cardiopulmonary resuscitation in patients with serum cell adhesion molecules in -1 were higher than those in healthy control group (P<0.05) ; and the longer the cardiopulmonary resuscitation in pa-tients with venous serum intercellular adhesion molecule -1 is higher(P<0.05). Conclusion The level of serum in pa-tients with cardiopulmonary resuscitation of cell adhesion molecule -1 will increase obviously, cardiopulmonary resus-citation earlier implementation, the levels of ICAM-1 were lower, the better the prognosis(P<0.05).