CAJ | 학술논문

目的：观察结直肠癌合并2型糖尿病围手术期采用持续皮下胰岛素泵输注(CSII)控制血糖的临床疗效。方法选择60例拟行手术治疗的结直肠癌合并2型糖尿病患者,随机分为治疗组和对照组,每组各30例,治疗组采用CSII治疗(CSII组),对照组采用常规多次皮下注射(MSII组)治疗,观察目标血糖达标时间、治疗前后两组血糖值、术中血糖、胰岛素用量、术前准备时间、低血糖发生率、伤口愈合情况、感染发生率住院总时间等临床指标。结果治疗后两组各点血糖水平明显下降,效果满意。治疗后CSII组餐前血糖、早餐后2 h血糖、睡前血糖均较MSII组低,CSII组血糖达标所用时间、胰岛素用量、术前准备时间、住院总时间、伤口愈合情况及感染发生率均低于MSII组,低血糖发生率、术中血糖两组无明显差异。结论 CSII在结直肠癌合并2型糖尿病患者围手术期中的疗效及安全性方面均优于MSII,值得推广。
목적：관찰결직장암합병2형당뇨병위수술기채용지속피하이도소빙수주(CSII)공제혈당적림상료효。방법선택60례의행수술치료적결직장암합병2형당뇨병환자,수궤분위치료조화대조조,매조각30례,치료조채용CSII치료(CSII조),대조조채용상규다차피하주사(MSII조)치료,관찰목표혈당체표시간、치료전후량조혈당치、술중혈당、이도소용량、술전준비시간、저혈당발생솔、상구유합정황、감염발생솔주원총시간등림상지표。결과치료후량조각점혈당수평명현하강,효과만의。치료후CSII조찬전혈당、조찬후2 h혈당、수전혈당균교MSII조저,CSII조혈당체표소용시간、이도소용량、술전준비시간、주원총시간、상구유합정황급감염발생솔균저우MSII조,저혈당발생솔、술중혈당량조무명현차이。결론 CSII재결직장암합병2형당뇨병환자위수술기중적료효급안전성방면균우우MSII,치득추엄。
Objective To observe the clinical efficacy of control blood glucose by using CSII for the people who suf-fers?from colorectal cancer complicated with type 2 diabetes mellitus in peri-operation period. Methods Sixty patients who sufferred from colorectal cancer complicated with type 2 diabetes mellitus were selected and were randomly divid-ed into treatment group(30 cases) and control group(30 cases). The treatment group was treated with CSII (CSII group), while the control group was treated with conventional subcutaneous injection (MSII group). The blood glucose level be-fore and after treatment, blood glucose time required to reach the target, the incidence of hypoglycemia, insulin dosage, preoperative preparation time, time of hospitalization,the incidence of wound healing, and infection were detected. Re-sults Blood glucose levels of two groups decreased significantly after treatment, which reached effect satisfaction. The time of blood glucose control, the rate of hypoglycemia, insulin dosage, preoperative preparation time, hospitalization time,wound healing and infection rate of group CSII were lower than those of MSII group. Conclusion Efficacy and safety in peri-operative time of CSII in colorectal cancer operation with type 2 diabetes mellitus is superior to that of MSII.