医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
25期
174-175
,共2页
林伟%黄志俭%孙斐宇%吴爱群%郑秀璧%张江东%李娜娜
林偉%黃誌儉%孫斐宇%吳愛群%鄭秀璧%張江東%李娜娜
림위%황지검%손비우%오애군%정수벽%장강동%리나나
危重症支气管哮喘%气管插管%机械通气%危险因素
危重癥支氣管哮喘%氣管插管%機械通氣%危險因素
위중증지기관효천%기관삽관%궤계통기%위험인소
Severe asthma%Intubation%Mechanical ventilation%Risk factors
目的研究探讨致危重症哮喘气管插管机械通气的危险因素，加深对此类危重症哮喘的认识和诊治经验。方法回顾性收集分析2010年1月~2013年2月入我院的危重症哮喘患者的临床资料，将其分为气管插管通气组和常规治疗组，分析比较两组的临床资料。结果最终有42例危重症支气管哮喘患者纳入本研究，其中常规治疗者26例(A组)，行气管插管机械通气治疗者16例(B组)，单因素分析表明B组中既往有气管插管史、激素依赖、依从性差患者所占比例，病死率及并发症发生率均显著高于常规治疗组(<0.05)。糖皮质激素的用量、住院时间也显著高于A组(<0.05)，而年龄、性别等因素两组无显著性差异。结论既往有气管插管病史、激素依赖、依从性差可能是导致危重症支气管哮喘气管插管的危险因素，接受气管插管机械通气的患者病情更为危重，病死率高，需引起足够的重视。
目的研究探討緻危重癥哮喘氣管插管機械通氣的危險因素，加深對此類危重癥哮喘的認識和診治經驗。方法迴顧性收集分析2010年1月~2013年2月入我院的危重癥哮喘患者的臨床資料，將其分為氣管插管通氣組和常規治療組，分析比較兩組的臨床資料。結果最終有42例危重癥支氣管哮喘患者納入本研究，其中常規治療者26例(A組)，行氣管插管機械通氣治療者16例(B組)，單因素分析錶明B組中既往有氣管插管史、激素依賴、依從性差患者所佔比例，病死率及併髮癥髮生率均顯著高于常規治療組(<0.05)。糖皮質激素的用量、住院時間也顯著高于A組(<0.05)，而年齡、性彆等因素兩組無顯著性差異。結論既往有氣管插管病史、激素依賴、依從性差可能是導緻危重癥支氣管哮喘氣管插管的危險因素，接受氣管插管機械通氣的患者病情更為危重，病死率高，需引起足夠的重視。
목적연구탐토치위중증효천기관삽관궤계통기적위험인소，가심대차류위중증효천적인식화진치경험。방법회고성수집분석2010년1월~2013년2월입아원적위중증효천환자적림상자료，장기분위기관삽관통기조화상규치료조，분석비교량조적림상자료。결과최종유42례위중증지기관효천환자납입본연구，기중상규치료자26례(A조)，행기관삽관궤계통기치료자16례(B조)，단인소분석표명B조중기왕유기관삽관사、격소의뢰、의종성차환자소점비례，병사솔급병발증발생솔균현저고우상규치료조(<0.05)。당피질격소적용량、주원시간야현저고우A조(<0.05)，이년령、성별등인소량조무현저성차이。결론기왕유기관삽관병사、격소의뢰、의종성차가능시도치위중증지기관효천기관삽관적위험인소，접수기관삽관궤계통기적환자병정경위위중，병사솔고，수인기족구적중시。
Objective To investigate the risk factors for intubation in patients with severe asthma for deepening recognition and therapeutic experience. Methods We retrospectively col ected and analyzed the clinical information of patients with severe asthma admit ed to our hospital from Jan, 2010 to Feb, 2013. We divided the patients into tow groups, one group is receiving normal treatments (A group) ,the other is receiving intubation and mechanical ventilation (B group). Clinical data in tow groups were compared and analyzed. Results There were 42 patients included in our study, of them, 26 patients who received normal treatments, 16 patients who received intubation and mechanical ventilation. Univariate analysis demonstrated that the ratio of history of intubation, steroid dependence, poor compliance , mortality and the rate of complication in group A patients were significantly higher than group B ( <0.05). The dosage of steroid and duration of hospitalization in group A patiens were markedly higher than group B ( <0.05).There were no significant dif erence in age and gender between tow group. Conclusion History of intubation, corticosteroid dependence and poor compliance maybe the risk factors leading to intubation and receiving mechanical ventilation. Patients with severe asthma who require intubation and mechanical ventilation have higher morbidity, and the condition are more severe. Great at ention should be paid.
