CAJ | 학술논문

目的观察米非司酮治疗子宫内膜异位(EMS)的临床疗效。方法38例确诊子宫内膜异位的患者,月经周期第2 d起服用米非司酮,1次/d,12.5 mg/次,3个月为1个疗程,1~2个疗程后比较治疗前后患者症状、体征、血清激素水平及不良反应情况。结果用药3个月后患者痛经等症状有所改善,有效率达93%。用药后后陷凹结节缩小,子宫活动度改善,卵巢囊肿缩小,观察米非司酮治疗子宫内膜异位(EMS)的临床疗效差异有统计学意义(<0.05)。结论小剂量米非司酮治疗子宫内膜异位疗效确切且安全,副反应较少,费用低,具有推广运用价值。
목적관찰미비사동치료자궁내막이위(EMS)적림상료효。방법38례학진자궁내막이위적환자,월경주기제2 d기복용미비사동,1차/d,12.5 mg/차,3개월위1개료정,1~2개료정후비교치료전후환자증상、체정、혈청격소수평급불량반응정황。결과용약3개월후환자통경등증상유소개선,유효솔체93%。용약후후함요결절축소,자궁활동도개선,란소낭종축소,관찰미비사동치료자궁내막이위(EMS)적림상료효차이유통계학의의(<0.05)。결론소제량미비사동치료자궁내막이위료효학절차안전,부반응교소,비용저,구유추엄운용개치。
Objective Observe mifepristone in the treatment of endometriosis (EMS) of clinical ef icacy.Methods 38 cases diagnosed patients with endometriosis, menstrual cycle 2 day taking mifepristone, 1/d, 12.5 mg/time, 3 months for a period of treatment, after one or two more patients before and after treatment symptoms and signs, serum hormone levels and adverse reactions.Results Medication after 3 months in patients with dysmenorrhea symptoms such as improved, 93% ef icient. After excavation nodules after narrowing, uterine activity improvement, ovarian cyst, observe mifepristone in the treatment of endometriosis (EMS) the clinical curative ef ect of the dif erence was statistical y significant ( <0.05).Conclusion Smal doses of mifepristone in the treatment of endometriosis curative ef ect and security, less side ef ect, low cost, has the promotion use value.