CAJ | 학술논문

目的：研究大鲵低聚糖肽抗皮肤光老化的临床疗效，以期为开发大鲵低聚糖肽化妆品提供基础数据。方法对40名面部出现光老化的女性受试者应用导入仪，导入大鲵低聚糖肽复合粉5-10分钟，即刻外敷仙鲵活性膜，连续治疗8次，每次间隔三天，医生和受试者对研究前后受试者的面部皮肤变化进行主观评价，再应用VISIA皮肤图像分析系统对受试者研究前后皮肤变化进行分析。结果 VISIA皮肤图像分析系统结果显示受试者在治疗后，面部细小皱纹数量减少、紫外线色素斑含量减少及棕色斑数目也有改善；医生对治疗效果评价：明显改善者3例(7.5%)，中度改善者21例（52.5%），轻度改善者13例（32.5%），无改善3例（7.5%），总改善率为92.5%；受试者非常满意者6人，满意者27人，总满意率为82.5%。结论光老化是由于皮肤长期受到日光照射所引起的损害，表现为皮肤粗糙、增厚、松弛、深而粗的皱纹，局部有过度的色素沉着或毛细血管扩张等，本研究通过大鲵低聚糖肽复合粉导入液来改善皮肤光老化情况，结果显示，大鲵低聚糖肽具有减轻面部色斑、改善皱纹、缓解紫外线对皮肤的影响，具有修复皮肤，延缓皮肤衰老的作用。
목적：연구대예저취당태항피부광노화적림상료효，이기위개발대예저취당태화장품제공기출수거。방법대40명면부출현광노화적녀성수시자응용도입의，도입대예저취당태복합분5-10분종，즉각외부선예활성막，련속치료8차，매차간격삼천，의생화수시자대연구전후수시자적면부피부변화진행주관평개，재응용VISIA피부도상분석계통대수시자연구전후피부변화진행분석。결과 VISIA피부도상분석계통결과현시수시자재치료후，면부세소추문수량감소、자외선색소반함량감소급종색반수목야유개선；의생대치료효과평개：명현개선자3례(7.5%)，중도개선자21례（52.5%），경도개선자13례（32.5%），무개선3례（7.5%），총개선솔위92.5%；수시자비상만의자6인，만의자27인，총만의솔위82.5%。결론광노화시유우피부장기수도일광조사소인기적손해，표현위피부조조、증후、송이、심이조적추문，국부유과도적색소침착혹모세혈관확장등，본연구통과대예저취당태복합분도입액래개선피부광노화정황，결과현시，대예저취당태구유감경면부색반、개선추문、완해자외선대피부적영향，구유수복피부，연완피부쇠로적작용。
Objective to study The giant salamander oligosaccharides peptides clinical efficacy of anti-skin photoaging,In order to provide the basic data for the development of the the giant salamander oligosaccharides peptide cosmetics. Methods forty patients with facial appear light aging female subjects application import instrument, Import the giant salamander oligosaccharides peptide compound powder (the cents salamander active hormone) 5-10 minutes , Immediately topical cents salamander active hormone mask, continuous treatment eight times, each time interval three days, The doctor and subjectsto study subjects before and after the facial skin changes of subjective evaluation, and then application VISIA skin perspective analysis system to study subjects before and after the skin change to carry on the analysis. Results through the research and contrast, VISIA results show that participants in the study wrinkles, UV pigment spots and brown spot is prior to significantly improve; The doctor evaluation obvious improver of three cases(7.5%), moderate improver of twenty-one cases (52.5%), mild improver of thirteen cases (32.5%);No improver of three cases (7.5%),The overall improvement rate was 92.5%.Participants satisfaction rate is 82.5%.Conclusions the giant salamander oligosaccharides peptide compound powder (the cents salamander active hormone) joint amplitude porcelain muscle biological fiber mask has obvious resistance to ultraviolet rays, splash, wrinkle, improve the effect of delay skin aging.