CAJ | 학술논문

从研究历史、应用现状、类型划分、菌株使用和考察因素5方面对应用于湿热灭菌的生物指示剂进行了分析。发现目前市售生物指示剂生产使用环节中缺乏关键因素 D 值的测定，建议由第三方提供技术支持衔接完善。同时，对生物指示剂深入的探索和开发，才能够实现其在灭菌工艺验证整体环节中的应用。
종연구역사、응용현상、류형화분、균주사용화고찰인소5방면대응용우습열멸균적생물지시제진행료분석。발현목전시수생물지시제생산사용배절중결핍관건인소 D 치적측정，건의유제삼방제공기술지지함접완선。동시，대생물지시제심입적탐색화개발，재능구실현기재멸균공예험증정체배절중적응용。
Based on the literature review and investigation and study of early days,the application of bio-indicators in moist heat sterilization of was analyzed in five aspects:history of study,application status,differentiation of type, use of strains,and investigation factors. It was found that current available commercially bio-indicators are lack of key factor-D value measurement in production and utilization,so it is recommended that technical support could be provid-ed by a third party to for complete linkage. Meanwhile,the deepening of exploration and development could be real-ized the application of bio-indicators in the whole link of sterilization technology verification.