CAJ | 학술논문

3-羟基丁酮及氧化还原产物是重要的4碳平台化合物，以糖质原料为底物的生物法制备是当今研究与生产的主流。介绍了3-羟基丁酮及氧化还原产物2，3-丁二醇、丁二酮产生的主要细菌，这些细菌积累3-羟基丁酮及氧化还原产物的代谢途径，主要的代谢及调控方式，代谢关键酶：乙酰乳酸合成酶、α-乙酰乳酸脱羧酶、2，3-丁二醇脱氢酶的结构与功能等国内外研究进展；并对3-羟基丁酮及氧化还原产物细菌代谢、发酵制备的未来研究提出了展望。
3-간기정동급양화환원산물시중요적4탄평태화합물，이당질원료위저물적생물법제비시당금연구여생산적주류。개소료3-간기정동급양화환원산물2，3-정이순、정이동산생적주요세균，저사세균적루3-간기정동급양화환원산물적대사도경，주요적대사급조공방식，대사관건매：을선유산합성매、α-을선유산탈최매、2，3-정이순탈경매적결구여공능등국내외연구진전；병대3-간기정동급양화환원산물세균대사、발효제비적미래연구제출료전망。
Acetoin and its redox product,important C4 precursorcompounds,which produced by microbe transforma-tion with sugariness would be the main trend. In this paper,the species and strains accumulating acetoin,2,3-bu-tanediol and diacetyl was summarized and classed. The research progress of metabolic pathway,regulation and control for acetoin and its redox product was also reported. Meanwhile,the structure and function relationship of three key en-zyme for the metabolites,α-acetoactate synthase,α-acetoactate decarboxylase and 2,3-butanediol dehydrogenase was concluded,and the further research and fermentation aspect for acetoin and its redox product metabolism in bacteria was proposed.