蚌埠医学院学报
蚌埠醫學院學報
방부의학원학보
ACTA ACADEMIAE MEDICINAE BENGBU
2014年
8期
1067-1069
,共3页
支原体肺炎%阿奇霉素%肺通气功能
支原體肺炎%阿奇黴素%肺通氣功能
지원체폐염%아기매소%폐통기공능
mycoplasmal pneumonia%azithromycin%pulmonary ventilation function
目的：探讨阿奇霉素治疗儿童支原体肺炎的疗效。方法：将支原体肺炎患儿50例随机分为2组。对照组25例,给予红霉素30 mg/kg,每天1次,连续5 d,停药2 d为1个疗程。观察组25例,给予阿奇霉素10 mg/kg,每天1次,连续5 d,停药2 d为1个疗程。比较2组患儿的疗效和肺通气功能变化。结果：观察组患儿的总有效率96.0%,高于对照组的76.0%( P<0.05)；观察组患儿咳嗽消失时间、罗音消失时间和住院时间均明显短于对照组(P<0.01)；2个疗程后观察组的用力肺活量和用力1 s肺活量均明显高于对照组(P<0.01)；观察组胃肠道反应少于对照组(P<0.05)。结论：阿奇霉素治疗儿童支原体肺炎的疗效确切,可缩短临床症状、体征的缓解时间以及疗程和住院时间,减少不良反应,有效改善肺功能。
目的：探討阿奇黴素治療兒童支原體肺炎的療效。方法：將支原體肺炎患兒50例隨機分為2組。對照組25例,給予紅黴素30 mg/kg,每天1次,連續5 d,停藥2 d為1箇療程。觀察組25例,給予阿奇黴素10 mg/kg,每天1次,連續5 d,停藥2 d為1箇療程。比較2組患兒的療效和肺通氣功能變化。結果：觀察組患兒的總有效率96.0%,高于對照組的76.0%( P<0.05)；觀察組患兒咳嗽消失時間、囉音消失時間和住院時間均明顯短于對照組(P<0.01)；2箇療程後觀察組的用力肺活量和用力1 s肺活量均明顯高于對照組(P<0.01)；觀察組胃腸道反應少于對照組(P<0.05)。結論：阿奇黴素治療兒童支原體肺炎的療效確切,可縮短臨床癥狀、體徵的緩解時間以及療程和住院時間,減少不良反應,有效改善肺功能。
목적：탐토아기매소치료인동지원체폐염적료효。방법：장지원체폐염환인50례수궤분위2조。대조조25례,급여홍매소30 mg/kg,매천1차,련속5 d,정약2 d위1개료정。관찰조25례,급여아기매소10 mg/kg,매천1차,련속5 d,정약2 d위1개료정。비교2조환인적료효화폐통기공능변화。결과：관찰조환인적총유효솔96.0%,고우대조조적76.0%( P<0.05)；관찰조환인해수소실시간、라음소실시간화주원시간균명현단우대조조(P<0.01)；2개료정후관찰조적용력폐활량화용력1 s폐활량균명현고우대조조(P<0.01)；관찰조위장도반응소우대조조(P<0.05)。결론：아기매소치료인동지원체폐염적료효학절,가축단림상증상、체정적완해시간이급료정화주원시간,감소불량반응,유효개선폐공능。
Objective:To investigate the clinical efficacy of azithromycin in the treatment of mycoplasmal pneumonia. Methods:Fifty children with mycoplasmal pneumonia were randomly divided into two groups. The 25 cases in the control group received the therapy of erythromycin 30 mg/kg,1 time/day,continuously for 5 days and a 2-day withdrawal as one course,and the 25 cases in the observation group azithromycin 10 mg/kg,1 time/day,continuously for 5 days and a 2-day withdrawal as one course. The clinical efficacy and changes of pulmonary ventilation function were compared between the two groups. Results:The total response rate of the observation group was 96. 0%,which was higher than that of the control(76. 0%)(P<0. 05). The time of cough disappearing,rales disappearing and hospital stay of the observation group was shorter than that of the control group(P<0. 01);the Forced vital capacity and Forced expiratory volume in 1 second of the observation group were higher than those of the control group after 2 months’ treatment( P<0. 01);the gastrointestinal reaction of the observation group was less than that of the control group(P<0. 05). Conclusions:The clinical efficacy of azithromycin is confirmed for treatment of mycoplasmal pneumonia. It may shorten the duration of the clinical symptoms and signs,decrease the treatment time and hospital stay,reduce the adverse reaction and improve the lung function.
