中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
EVALUATION AND ANAL YSIS OF DRUG-USE IN HOSPITALS OF CHINA
2014年
9期
848-850
,共3页
抗菌药物%药品不良反应%合理用药
抗菌藥物%藥品不良反應%閤理用藥
항균약물%약품불량반응%합리용약
Antibiotics%Adverse drug reaction%Rational use of drug
目的：了解抗菌药物所致药品不良反应（ADR）发生的特点，为临床合理用药提供参考。方法：收集我院2007-2013年收集上报至国家ADR监测网的抗菌药物所致ADR报告225例进行回顾性分析。结果：225例ADR报告中，共涉及7大类27个品种抗菌药物。其中头孢菌素类所致的ADR居首位（44.58％）；静脉滴注（97.50％）给药途径最容易引发ADR；ADR累及器官或系统以皮肤及其附件损害最为常见（56.33％）。结论：应重视抗菌药物的合理使用，加强ADR报告和监测工作，以减少ADR的发生，保障患者用药安全。
目的：瞭解抗菌藥物所緻藥品不良反應（ADR）髮生的特點，為臨床閤理用藥提供參攷。方法：收集我院2007-2013年收集上報至國傢ADR鑑測網的抗菌藥物所緻ADR報告225例進行迴顧性分析。結果：225例ADR報告中，共涉及7大類27箇品種抗菌藥物。其中頭孢菌素類所緻的ADR居首位（44.58％）；靜脈滴註（97.50％）給藥途徑最容易引髮ADR；ADR纍及器官或繫統以皮膚及其附件損害最為常見（56.33％）。結論：應重視抗菌藥物的閤理使用，加彊ADR報告和鑑測工作，以減少ADR的髮生，保障患者用藥安全。
목적：료해항균약물소치약품불량반응（ADR）발생적특점，위림상합리용약제공삼고。방법：수집아원2007-2013년수집상보지국가ADR감측망적항균약물소치ADR보고225례진행회고성분석。결과：225례ADR보고중，공섭급7대류27개품충항균약물。기중두포균소류소치적ADR거수위（44.58％）；정맥적주（97.50％）급약도경최용역인발ADR；ADR루급기관혹계통이피부급기부건손해최위상견（56.33％）。결론：응중시항균약물적합리사용，가강ADR보고화감측공작，이감소ADR적발생，보장환자용약안전。
OBJECTIVE:To investigate the characteristics of antibiotic-induced adverse drug reactions (ADRs) so as to pro-vide reference for clinical rational use of antibiotics. METHODS:A total of 225 ADR cases submitted by our hospital to National ADR Monitoring network during 2007-2013 period were retrospectively analyzed. RESULTS:7 categories and 27 antibiotics were involved in the 225 ADR cases. The ADR cases induced by cephalosporins dominated the first place(44.58%),induced mostly by drip infusion (97.50%) and manifested mostly as lesions of skin and its appendages (56.33%). CONCLUSIONS:Great impor-tance should be attached to rational use of antibiotics as well as strengthening ADR reporting and monitoring so as to reduce the oc-currence of ADR and ensure patients’medication safety.
