中国康复理论与实践
中國康複理論與實踐
중국강복이론여실천
CHINESE JOURNAL OF REHABILITATION THEORY & PRACTICE
2014年
9期
890-891
,共2页
创伤性颅脑损伤%早期康复%基质金属蛋白酶
創傷性顱腦損傷%早期康複%基質金屬蛋白酶
창상성로뇌손상%조기강복%기질금속단백매
traumatic brain injury%early rehabilitation%matrix metalloproteinases
目的：探讨早期康复训练对创伤性颅脑损伤患者血清中基质金属蛋白酶(MMP)的作用。方法创伤性颅脑损伤患者分为两组，对照组(n=45)应用常规治疗，观察组(n=45)在常规治疗的基础上加用早期康复训练。观察两组疗效及治疗4周后患者血清MMP-2和MMP-9水平。结果观察组的显效率明显优于对照组(P<0.01)。观察组治疗后血清MMP-2和MMP-9水平下降多于对照组(P<0.05)。结论早期康复训练能有效下调血清中MMP的表达，促进神经细胞功能的恢复。
目的：探討早期康複訓練對創傷性顱腦損傷患者血清中基質金屬蛋白酶(MMP)的作用。方法創傷性顱腦損傷患者分為兩組，對照組(n=45)應用常規治療，觀察組(n=45)在常規治療的基礎上加用早期康複訓練。觀察兩組療效及治療4週後患者血清MMP-2和MMP-9水平。結果觀察組的顯效率明顯優于對照組(P<0.01)。觀察組治療後血清MMP-2和MMP-9水平下降多于對照組(P<0.05)。結論早期康複訓練能有效下調血清中MMP的錶達，促進神經細胞功能的恢複。
목적：탐토조기강복훈련대창상성로뇌손상환자혈청중기질금속단백매(MMP)적작용。방법창상성로뇌손상환자분위량조，대조조(n=45)응용상규치료，관찰조(n=45)재상규치료적기출상가용조기강복훈련。관찰량조료효급치료4주후환자혈청MMP-2화MMP-9수평。결과관찰조적현효솔명현우우대조조(P<0.01)。관찰조치료후혈청MMP-2화MMP-9수평하강다우대조조(P<0.05)。결론조기강복훈련능유효하조혈청중MMP적표체，촉진신경세포공능적회복。
Objective To investigate the effect of early rehabilitation on serum matrix metalloproteinases (MMP) in patients with trau-matic brain injury. Methods Patients with traumatic brain injury were divided into control group (n=45), who accepted routine treatment, and observation group (n=45), who accepted early rehabilitation in addition. The incidences of improvement were compared, and the serum level of MMP-2 and MMP-9 were measured before and 4 weeks after treatment. Results The incidence of improvement was more in the ob-servation group than in the control group (P<0.01). The serum level of MMP-2 and MMP-9 decreased more in the observation group than in the control gorup (P<0.05). Conclusion Early rehabilitation can reduce the level of MMP and promote the function recovery in patients with traumatic brain injury.
