医药导报
醫藥導報
의약도보
HERALD OF MEDICINE
2014年
9期
1154-1156
,共3页
红毛悬钩子%化学成分%硅胶柱层析法
紅毛懸鉤子%化學成分%硅膠柱層析法
홍모현구자%화학성분%규효주층석법
Rubus pinfaensis%Chemical constituents%Silica gel column chromatography
目的：研究红毛悬钩子根的化学成分。方法采用硅胶柱层析法对湖北产蔷薇科悬钩子属红毛悬钩子( Rubus pinfaensis)干燥根醇提物进行分离,经IR、1 H-NMR和EI-MS等波谱进行结构分析。结果鉴定出5种化合物,分别为齐墩果酸(oleanolic acid)(Ⅰ)、3-keto,16α-hydroxy,24-noroleanolic acid(Ⅱ)、3'-甲氧基杨梅黄酮(Ⅲ)、尿嘧啶脱氧核苷(2'-deoxyuridine)(Ⅳ)和对羟基苯乙酸(Ⅴ)。结论化合物Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ均为首次从红毛悬钩子根中分离得到。
目的：研究紅毛懸鉤子根的化學成分。方法採用硅膠柱層析法對湖北產薔薇科懸鉤子屬紅毛懸鉤子( Rubus pinfaensis)榦燥根醇提物進行分離,經IR、1 H-NMR和EI-MS等波譜進行結構分析。結果鑒定齣5種化閤物,分彆為齊墩果痠(oleanolic acid)(Ⅰ)、3-keto,16α-hydroxy,24-noroleanolic acid(Ⅱ)、3'-甲氧基楊梅黃酮(Ⅲ)、尿嘧啶脫氧覈苷(2'-deoxyuridine)(Ⅳ)和對羥基苯乙痠(Ⅴ)。結論化閤物Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ均為首次從紅毛懸鉤子根中分離得到。
목적：연구홍모현구자근적화학성분。방법채용규효주층석법대호북산장미과현구자속홍모현구자( Rubus pinfaensis)간조근순제물진행분리,경IR、1 H-NMR화EI-MS등파보진행결구분석。결과감정출5충화합물,분별위제돈과산(oleanolic acid)(Ⅰ)、3-keto,16α-hydroxy,24-noroleanolic acid(Ⅱ)、3'-갑양기양매황동(Ⅲ)、뇨밀정탈양핵감(2'-deoxyuridine)(Ⅳ)화대간기분을산(Ⅴ)。결론화합물Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ균위수차종홍모현구자근중분리득도。
Objective To study the chemical constituents from dry roots of Rubus pinfaensis. Methods The compounds were separated from alcohol extracts of the roots of Rubus pinfaensis with silica gel column chromatography,and identified using IR,1 H-NMR and EI-MS methods. Results Five compounds were isolated and identified as oleanolic acid (Ⅰ) ,3-keto,16α-hydroxy,24-noroleanolic acid (II) , 3 '-methoxy myricetin (Ⅲ) , 2 '-deoxyuridine (Ⅳ) and p-hydroxybenzoic acid (Ⅴ) . Conclusion CompoundsⅠ,II,Ⅲ,ⅣandⅤwere isolated from Rubus pinfaensis for the first time.
