国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2013年
6期
412-414
,共3页
安英俊%张祥杰%李平%李红义
安英俊%張祥傑%李平%李紅義
안영준%장상걸%리평%리홍의
降钙素原%C-反应蛋白%血沉%细菌感染
降鈣素原%C-反應蛋白%血沉%細菌感染
강개소원%C-반응단백%혈침%세균감염
Procalcitonin%C-reactive protein%Erythrocyte sedimentation rate%Bacterial infection
目的 探讨血清降钙素原(PCT)、C-反应蛋白(CRP)、血沉(ESR)联合定量检测在下呼吸道感染诊断及预后评估的指导意义.方法 选取2011年10月至2012年6月在我科住院的145例下呼吸道感染并有痰培养病原菌明确的病例,同期健康对照组41名.采用全自动免疫透视比浊法测定CRP水平,采用双抗体夹心免疫半定量快速实验(胶体金法)测定PCT水平,采用魏氏(Westergren)法测定ESR水平.结果 与健康对照组相比较,下呼吸道感染患者的PCT、CRP、ESR显著升高(P＜0.01).细菌感染组患者的PCT、CRP、ESR明显高于非细菌感染组(病毒、真菌及其他病原体)(P＜0.01).PCT水平随着感染的控制而明显下降,有助于判断预后.结论 CRP、PCT及ESR的常规检测有助于细菌感染的早期诊断,对及时合理应用抗生素及评估细菌感染性疾病的预后有重要的意义.
目的 探討血清降鈣素原(PCT)、C-反應蛋白(CRP)、血沉(ESR)聯閤定量檢測在下呼吸道感染診斷及預後評估的指導意義.方法 選取2011年10月至2012年6月在我科住院的145例下呼吸道感染併有痰培養病原菌明確的病例,同期健康對照組41名.採用全自動免疫透視比濁法測定CRP水平,採用雙抗體夾心免疫半定量快速實驗(膠體金法)測定PCT水平,採用魏氏(Westergren)法測定ESR水平.結果 與健康對照組相比較,下呼吸道感染患者的PCT、CRP、ESR顯著升高(P＜0.01).細菌感染組患者的PCT、CRP、ESR明顯高于非細菌感染組(病毒、真菌及其他病原體)(P＜0.01).PCT水平隨著感染的控製而明顯下降,有助于判斷預後.結論 CRP、PCT及ESR的常規檢測有助于細菌感染的早期診斷,對及時閤理應用抗生素及評估細菌感染性疾病的預後有重要的意義.
목적 탐토혈청강개소원(PCT)、C-반응단백(CRP)、혈침(ESR)연합정량검측재하호흡도감염진단급예후평고적지도의의.방법 선취2011년10월지2012년6월재아과주원적145례하호흡도감염병유담배양병원균명학적병례,동기건강대조조41명.채용전자동면역투시비탁법측정CRP수평,채용쌍항체협심면역반정량쾌속실험(효체금법)측정PCT수평,채용위씨(Westergren)법측정ESR수평.결과 여건강대조조상비교,하호흡도감염환자적PCT、CRP、ESR현저승고(P＜0.01).세균감염조환자적PCT、CRP、ESR명현고우비세균감염조(병독、진균급기타병원체)(P＜0.01).PCT수평수착감염적공제이명현하강,유조우판단예후.결론 CRP、PCT급ESR적상규검측유조우세균감염적조기진단,대급시합리응용항생소급평고세균감염성질병적예후유중요적의의.
Objective To investigate the diagnosis and prognosis significance of joint detection of serum procalcitonin (PCT),C-reactive protein (CRP),and erythrocyte sedimentation rate (ESR) in lower respiratory tract infection.Methods From October 2011 to June 2012,145 cases of lower respiratory tract infection hospitalized in our department with clear pathogens by sputum culture were collected,and there were 41 cases in the healthy control group.CRP level was detected by automated immunoassay perspective turbidimetry,PCT level was determined by semi-quantitative rapid experimental double-antibody sandwich immunoassay (colloidal gold),and ESR was examined by Westergren.Results Compared with healthy people,PCT,CRP,and ESR were significantly increased in patients with lower respiratory tract infections (P ＜0.01).PCT,CRP,and ESR in patients with bacterial infection were higher than those in patients of non-bacterial infection (viruses,fungi,and other pathogens) (P ＜ 0.01).PCT level significantly decreased with infection control,which was helpful for the judgment of prognosis.Conclusions CRP,PCT,and ESR routine testing helps early diagnosis of bacterial infections,has important significance for timely and reasonable use of antibiotics,and the prognostic assessment of bacterial infectious diseases.
