医学研究生学报
醫學研究生學報
의학연구생학보
JOURNAL OF MEDICAL POSTGRADUATE
2014年
9期
998-1001
,共4页
朱亚非(综述)%包玲(审校)
硃亞非(綜述)%包玲(審校)
주아비(종술)%포령(심교)
肺表面活性蛋白D%生理功能%呼吸道合胞病毒感染
肺錶麵活性蛋白D%生理功能%呼吸道閤胞病毒感染
폐표면활성단백D%생리공능%호흡도합포병독감염
Surfactant protein D%Physiological function%Respiratory syncytial virus infections
肺表面活性蛋白( surfactant protein , SP)-D在机体肺部防御和先天性免疫方面发挥着重要作用。目前的研究表明,SP-D参与儿童呼吸道合胞病毒( respiratory syncytial virus , RSV)感染的发生、发展,提示SP-D可能成为治疗肺部炎症性疾病的有效手段。文中就SP-D结构、功能及其与RSV关系、对肺部炎症性疾病治疗方面作一综述,旨在为RSV感染的治疗提供依据。
肺錶麵活性蛋白( surfactant protein , SP)-D在機體肺部防禦和先天性免疫方麵髮揮著重要作用。目前的研究錶明,SP-D參與兒童呼吸道閤胞病毒( respiratory syncytial virus , RSV)感染的髮生、髮展,提示SP-D可能成為治療肺部炎癥性疾病的有效手段。文中就SP-D結構、功能及其與RSV關繫、對肺部炎癥性疾病治療方麵作一綜述,旨在為RSV感染的治療提供依據。
폐표면활성단백( surfactant protein , SP)-D재궤체폐부방어화선천성면역방면발휘착중요작용。목전적연구표명,SP-D삼여인동호흡도합포병독( respiratory syncytial virus , RSV)감염적발생、발전,제시SP-D가능성위치료폐부염증성질병적유효수단。문중취SP-D결구、공능급기여RSV관계、대폐부염증성질병치료방면작일종술,지재위RSV감염적치료제공의거。
The pulmonary surfactant protein D ( SP-D) plays an important role in host defense and innate immunity of the lung.It has increasing evidences that SP-D involves in the pathogenesis of respiratory syncytial virus (RSV)infection.Recent studies have demonstrated that SP-D can be used for treating infectious and inflammatory diseases of the lung .Here is to make a review on SP-D structure, function , relationship between RSV and pulmonary inflammatory disease treatment .aiming to provide some assistance for treatment of RSV infection .