CAJ | 학술논문

目的：观察中药灌肠联合银杏达莫注射液对糖尿病肾病（ DN）肾功能的影响。方法将130例DN患者随机分为2组。治疗组65例予中药灌肠联合银杏达莫注射液治疗，对照组65例予单纯西药缬沙坦胶囊治疗。2组均治疗10 d后观察疗效和肾功能变化情况。结果治疗组总有效率高于对照组（ P＜0．05），治疗组疗效优于对照组。2组治疗后血肌酐（Cr）、尿素氮（BUN）、24 h尿蛋白定量较本组治疗前均降低（ P＜0．05）；治疗组治疗后Cr、BUN、24 h尿蛋白定量较对照组治疗后降低（ P＜0．05）。结论中药灌肠联合银杏达莫注射液治疗DN能改善肾功能，延缓肾衰竭的进展。
목적：관찰중약관장연합은행체막주사액대당뇨병신병（ DN）신공능적영향。방법장130례DN환자수궤분위2조。치료조65례여중약관장연합은행체막주사액치료，대조조65례여단순서약힐사탄효낭치료。2조균치료10 d후관찰료효화신공능변화정황。결과치료조총유효솔고우대조조（ P＜0．05），치료조료효우우대조조。2조치료후혈기항（Cr）、뇨소담（BUN）、24 h뇨단백정량교본조치료전균강저（ P＜0．05）；치료조치료후Cr、BUN、24 h뇨단백정량교대조조치료후강저（ P＜0．05）。결론중약관장연합은행체막주사액치료DN능개선신공능，연완신쇠갈적진전。
Objective To observe the effect of Chinese medicine enema combined with Yinxingdamo injec-tion on the renal function of diabetic nephropathy ( DN) .Methods 130 cases of DN were randomly divided into two groups.65 cases in treatment group were treated by Chinese medicine enema combined with Yinxingdamo injection .65 cases in control group were given only Valsartan Capsules .The efficacy and renal function change were observed after 10 days of treatment .Results The total effective rate in treatment group was higher than that in control group ( P<0.05).Cr, BUN and 24h urine protein quantitation after treatment were decreased as compared with those before treatment in two groups (P<0.05).Cr, BUN and 24 h urine protein quantitation in treatment group were lower than those in control group after treatment (P<0.05).Conclusion Chinese medicine enema combined with Yinxing-damo injection on diabetic nephropathy can improve the renal function and delay the progression of chronic renal fail -ure.