北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2014年
10期
5-5,6
,共2页
骨康口服液%阿魏酸%高效液相色谱%质量控制
骨康口服液%阿魏痠%高效液相色譜%質量控製
골강구복액%아위산%고효액상색보%질량공제
Gukangkoufuye%Ferulic acid%HPLC%Quanlity control
目的：建立HPLC测定骨康口服液中阿魏酸的含量测定方法。方法：采用HPLC法测定阿魏酸的含量，Diamonsil C18（4.6mm×250mm，5μm）为色谱柱，流动相为乙腈-0.085%磷酸溶液（17∶83），流速1.0ml·min-1，检测波长316nm。结果：阿魏酸在6.205～24.82μg·ml-1呈良好的线性关系（r=1.0000）。回收率为98.22%（RSD 1.4%，n=9）。结论：本法简便，准确，灵敏度高，重现性好，能有效控制骨康口服液的质量。
目的：建立HPLC測定骨康口服液中阿魏痠的含量測定方法。方法：採用HPLC法測定阿魏痠的含量，Diamonsil C18（4.6mm×250mm，5μm）為色譜柱，流動相為乙腈-0.085%燐痠溶液（17∶83），流速1.0ml·min-1，檢測波長316nm。結果：阿魏痠在6.205～24.82μg·ml-1呈良好的線性關繫（r=1.0000）。迴收率為98.22%（RSD 1.4%，n=9）。結論：本法簡便，準確，靈敏度高，重現性好，能有效控製骨康口服液的質量。
목적：건립HPLC측정골강구복액중아위산적함량측정방법。방법：채용HPLC법측정아위산적함량，Diamonsil C18（4.6mm×250mm，5μm）위색보주，류동상위을정-0.085%린산용액（17∶83），류속1.0ml·min-1，검측파장316nm。결과：아위산재6.205～24.82μg·ml-1정량호적선성관계（r=1.0000）。회수솔위98.22%（RSD 1.4%，n=9）。결론：본법간편，준학，령민도고，중현성호，능유효공제골강구복액적질량。
Objective:To establish a quantitative method for ferulic acid in Gukangkoufuye by HPLC.Method: Using a HPLC method with Diamonsil C18 (4.6mm ×250mm,5μm), the mobile phase was acetonitrile-0.085% phosphoric acid solution (17∶83)at a flow rate of 1.0ml·min-1, the UV detection wavelength was 316 nm.Result: The linear range of ferulic acid was in the range between 6.205μg·ml-1 and 24.82μg·ml-1 (r=1.0000). The average recovery of ferulic acid was 98.22% with RSD of 1.4%.Conclusion: This method is simple, efficient and accurate, which can be used for the quality control of ferulic acid in Gukangkoufuye.
