CAJ | 학술논문

目的：分析清热利水方联合还原型谷胱甘肽（GSH）治疗瘀热水结型急性肾损伤（AKI）的临床疗效。方法36例重症患者均在入住ICU病房48 h内发生AKI，随机分为2组，均同时给予抗感染及对症支持治疗，A组18例，为清热利水方联合GSH治疗组，B组18例，为GSH治疗组。分析入住ICU第1、5、7、14天血肌酐、尿素氮、尿量变化情况。结果2组治疗前后的Scr、BUN及尿量变化均有统计学意义（P＜0.05）。结论清热利水方联合GSH对瘀热水结型AKI有确切的疗效。
목적：분석청열이수방연합환원형곡광감태（GSH）치료어열수결형급성신손상（AKI）적림상료효。방법36례중증환자균재입주ICU병방48 h내발생AKI，수궤분위2조，균동시급여항감염급대증지지치료，A조18례，위청열이수방연합GSH치료조，B조18례，위GSH치료조。분석입주ICU제1、5、7、14천혈기항、뇨소담、뇨량변화정황。결과2조치료전후적Scr、BUN급뇨량변화균유통계학의의（P＜0.05）。결론청열이수방연합GSH대어열수결형AKI유학절적료효。
Objective To analyze the effect of Qingrelishuifang and glutathione injection on patients with acute kidney injury(AKI) with the mixed stasis-heat and water syndrome.Methods 36 critical patients appeared AKI within 48 hours of in ICU were divided randomly into two groups.The group A(n=18)was received Qingrelishuifang and glutathione injection.The group B(n:18)was received glutathione injection only.To analyze the difference of Scr、BUN and urine volume respectively in the first、fifth、seventh and 14th day.Results The difference is of significance in Scr、BUN and urine volume(P<0.05). Conclusion Combination of Qingrelishuifang and glutathione injection has marked therapeutic effect on AKI with the mixed stasis-heat and water syndrome.