中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
26期
37-38,39
,共3页
加巴喷丁%术前用药%小儿
加巴噴丁%術前用藥%小兒
가파분정%술전용약%소인
Gabapentin%Premedication%Pediatric patients
目的：探讨加巴喷丁在小儿术前用药中的疗效。方法：择期手术患儿60例，随机分为三组：A组加巴喷丁20 mg/kg口服，B组咪达唑仑0.5 mg/kg+5 mL的10%GS混合液口服，C组苯巴比妥钠5 mg/kg肌注。观察三组患儿给药时接受配合情况，给药后的HR、RR、MAP、SpO2变化；患儿用药后的行为变化。结果：使用加巴喷丁和咪达唑仑作为术前给药的患儿在给药配合、生理循环稳定方面明显优于使用苯巴比妥钠的患儿。结论：加巴喷丁作用安全有效，围术期患儿血流动力学稳定，可作为小儿术前用药。
目的：探討加巴噴丁在小兒術前用藥中的療效。方法：擇期手術患兒60例，隨機分為三組：A組加巴噴丁20 mg/kg口服，B組咪達唑崙0.5 mg/kg+5 mL的10%GS混閤液口服，C組苯巴比妥鈉5 mg/kg肌註。觀察三組患兒給藥時接受配閤情況，給藥後的HR、RR、MAP、SpO2變化；患兒用藥後的行為變化。結果：使用加巴噴丁和咪達唑崙作為術前給藥的患兒在給藥配閤、生理循環穩定方麵明顯優于使用苯巴比妥鈉的患兒。結論：加巴噴丁作用安全有效，圍術期患兒血流動力學穩定，可作為小兒術前用藥。
목적：탐토가파분정재소인술전용약중적료효。방법：택기수술환인60례，수궤분위삼조：A조가파분정20 mg/kg구복，B조미체서륜0.5 mg/kg+5 mL적10%GS혼합액구복，C조분파비타납5 mg/kg기주。관찰삼조환인급약시접수배합정황，급약후적HR、RR、MAP、SpO2변화；환인용약후적행위변화。결과：사용가파분정화미체서륜작위술전급약적환인재급약배합、생리순배은정방면명현우우사용분파비타납적환인。결론：가파분정작용안전유효，위술기환인혈류동역학은정，가작위소인술전용약。
Objective:To evaluate the clinical efficacy of oral gabapentin for premedication in pediatric patients. Method:Sixty ASA I-II pediatric patients were randomly divided into three groups ,each of 20 patients.The A groups and the B groups were orally received gabapentin(20 mg/kg)and midazolam(0.5 mg/kg)respectively.The C groups were given intramuscularly injection of Phenobarbital sodium with 5 mg/kg.The assessment of medication compliance during the premedication and the anxiety behavior and neurobehavioral at separation from parents during venepuncture and induction were graded.In addition,HR,RR,and SpO2 were also recorded and evaluated.Result:Comparison of the C group,there were significant difference with the A and B group with the clinical effects.Conclusion:Gabapentin is effective and safe in pediatric patients as premedication.
