中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
26期
34-36
,共3页
心力衰竭%高血压%贝那普利%氨氯地平
心力衰竭%高血壓%貝那普利%氨氯地平
심력쇠갈%고혈압%패나보리%안록지평
Heart failure%Hypertension%Benazepril%Amlodipine
目的：评价贝那普利联合氨氯地平治疗高血压心力衰竭患者的疗效。方法：选取2011年1月-2012年8月在本院门诊和病房治疗的68例高血压心力衰竭患者，按照随机数字表法将其分为观察组和对照组各34例。观察组给予贝那普利（10 mg/d）联合氨氯地平（5 mg/d）治疗。对照组仅给予贝那普利治疗（10 mg/d），12周为一疗程。观察比较两组患者的降压效果及治疗前后左室舒张功能的变化。结果：两组治疗后的HR、SBP和DBP均明显低于治疗前，差异均有统计学意义（P<0.05），但两组间比较差异无统计学意义（P>0.05）。观察组治疗后的LVEDD缩小率、LVESD缩小率和LVEF改善率均明显高于对照组，差异均有统计学意义（P<0.05）。结论：贝那普利联合氨氯地平治疗能明显改善高血压心力衰竭患者左室功能，能够达到减少高血压患者心、脑、肾、血管并发症的发生，提高患者生活质量，疗效确切，效价比高，是较理想的降压药物。
目的：評價貝那普利聯閤氨氯地平治療高血壓心力衰竭患者的療效。方法：選取2011年1月-2012年8月在本院門診和病房治療的68例高血壓心力衰竭患者，按照隨機數字錶法將其分為觀察組和對照組各34例。觀察組給予貝那普利（10 mg/d）聯閤氨氯地平（5 mg/d）治療。對照組僅給予貝那普利治療（10 mg/d），12週為一療程。觀察比較兩組患者的降壓效果及治療前後左室舒張功能的變化。結果：兩組治療後的HR、SBP和DBP均明顯低于治療前，差異均有統計學意義（P<0.05），但兩組間比較差異無統計學意義（P>0.05）。觀察組治療後的LVEDD縮小率、LVESD縮小率和LVEF改善率均明顯高于對照組，差異均有統計學意義（P<0.05）。結論：貝那普利聯閤氨氯地平治療能明顯改善高血壓心力衰竭患者左室功能，能夠達到減少高血壓患者心、腦、腎、血管併髮癥的髮生，提高患者生活質量，療效確切，效價比高，是較理想的降壓藥物。
목적：평개패나보리연합안록지평치료고혈압심력쇠갈환자적료효。방법：선취2011년1월-2012년8월재본원문진화병방치료적68례고혈압심력쇠갈환자，안조수궤수자표법장기분위관찰조화대조조각34례。관찰조급여패나보리（10 mg/d）연합안록지평（5 mg/d）치료。대조조부급여패나보리치료（10 mg/d），12주위일료정。관찰비교량조환자적강압효과급치료전후좌실서장공능적변화。결과：량조치료후적HR、SBP화DBP균명현저우치료전，차이균유통계학의의（P<0.05），단량조간비교차이무통계학의의（P>0.05）。관찰조치료후적LVEDD축소솔、LVESD축소솔화LVEF개선솔균명현고우대조조，차이균유통계학의의（P<0.05）。결론：패나보리연합안록지평치료능명현개선고혈압심력쇠갈환자좌실공능，능구체도감소고혈압환자심、뇌、신、혈관병발증적발생，제고환자생활질량，료효학절，효개비고，시교이상적강압약물。
Objective:To evaluate the effect of benazepril combined with amlodipine in treatment of hypertensive heart failure.Method:68 patients with hypertensive heart failure out patient wards in our hospital from January 2011 to August 2012 were selected,they were divided into the control group and the observation group according to the random number table method,34 cases in each group.The observation group was given amlodipine(5 mg/d)combined with benazepril(10 mg/d),the control group was only given benazepril(10 mg/d).12 weeks for a course of treatment.The antihypertensive effect and left ventricular diastolic function changes before and after treatment of the two groups were observed and compared.Result:The HR,SBP and DBP of the two groups after treatment were significantly lower than those of control group,the differences were statistically significant(P<0.05).But there was no statistically significant difference between two groups(P>0.05).The LVEDD reduction rate,LVESD reduction rate and LVEF improvement rate of observation group were significantly higher than those of control group,the differences were statistically significant (P<0.05).Conclusion:Benazepril combined with amlodipine treatment can significantly improve left ventricular function in hypertensive patients with heart failure,can reduce hypertension in patients with heart,brain,kidney,vascular complications,improve the quality of life of patients,curative effect is exact,high titer,is an ideal antihypertensive drugs.
