世界最新医学信息文摘（连续型电子期刊）
世界最新醫學信息文摘（連續型電子期刊）
세계최신의학신식문적（련속형전자기간）
World Latest Medicine Information
2014年
26期
102-103
,共2页
血液透析%残余肾功能%胆固醇%血磷
血液透析%殘餘腎功能%膽固醇%血燐
혈액투석%잔여신공능%담고순%혈린
hemodialysis%residual renal function%cholesterol%phosphorus
目的：对维持性血液透析患者使用不同的血液净化方式，分析对残余肾功能（rrf)的影响。方法随机抽取我院进行常规血液透析的患者共44例，分为低通量血液透析组（lfHd组14例）、高通量血液透析组（HfHd组15例）及血液透析联合血液灌流组（Hd+HP组15例）。在患者入选时、治疗6个月后采集所有患者的血尿标本，对患者的相关指标进行检测。结果入选时三组患者之间的残余肾功能、血脂、血磷、β2微球蛋白没有统计学意义上的差异。经治疗6个月后患者的残余肾功能较入选时明显降低，但lfHd组残余肾功能下降率高于HfHd组和Hd+HP组。治疗后患者的血脂、血磷、β2微球蛋白，HfHd组和Hd+HP组明显低于lfHd组，HfHd组和Hd+HP组之间没有统计学意义上的差异。结论患者实施血液透析过程中，残余肾功能均有所下降，但HfHd组、Hd+HP组与lfHd组比较，残余肾功能下降率较低，同时与lfHd组相比，能够更好的降低血脂、血磷、β2微球蛋白水平。
目的：對維持性血液透析患者使用不同的血液淨化方式，分析對殘餘腎功能（rrf)的影響。方法隨機抽取我院進行常規血液透析的患者共44例，分為低通量血液透析組（lfHd組14例）、高通量血液透析組（HfHd組15例）及血液透析聯閤血液灌流組（Hd+HP組15例）。在患者入選時、治療6箇月後採集所有患者的血尿標本，對患者的相關指標進行檢測。結果入選時三組患者之間的殘餘腎功能、血脂、血燐、β2微毬蛋白沒有統計學意義上的差異。經治療6箇月後患者的殘餘腎功能較入選時明顯降低，但lfHd組殘餘腎功能下降率高于HfHd組和Hd+HP組。治療後患者的血脂、血燐、β2微毬蛋白，HfHd組和Hd+HP組明顯低于lfHd組，HfHd組和Hd+HP組之間沒有統計學意義上的差異。結論患者實施血液透析過程中，殘餘腎功能均有所下降，但HfHd組、Hd+HP組與lfHd組比較，殘餘腎功能下降率較低，同時與lfHd組相比，能夠更好的降低血脂、血燐、β2微毬蛋白水平。
목적：대유지성혈액투석환자사용불동적혈액정화방식，분석대잔여신공능（rrf)적영향。방법수궤추취아원진행상규혈액투석적환자공44례，분위저통량혈액투석조（lfHd조14례）、고통량혈액투석조（HfHd조15례）급혈액투석연합혈액관류조（Hd+HP조15례）。재환자입선시、치료6개월후채집소유환자적혈뇨표본，대환자적상관지표진행검측。결과입선시삼조환자지간적잔여신공능、혈지、혈린、β2미구단백몰유통계학의의상적차이。경치료6개월후환자적잔여신공능교입선시명현강저，단lfHd조잔여신공능하강솔고우HfHd조화Hd+HP조。치료후환자적혈지、혈린、β2미구단백，HfHd조화Hd+HP조명현저우lfHd조，HfHd조화Hd+HP조지간몰유통계학의의상적차이。결론환자실시혈액투석과정중，잔여신공능균유소하강，단HfHd조、Hd+HP조여lfHd조비교，잔여신공능하강솔교저，동시여lfHd조상비，능구경호적강저혈지、혈린、β2미구단백수평。
Objectiveto analyze the impact of different blood purification methods on residual renal function in maintenance hemodialysis patients. Methods 44 patients treated with hemodialysis were randomly selected in our hospital. they were divided into low-flux hemodialysis group (14 cases of lfHd group), high-flux hemodialysis group (15cases of HfHd group) and blood hemodialysis combined with hemoperfusion group (15 cases of Hd + HP group). When patients were enrolled, all patients’ urine specimens were collected after treatment for 6 months and the relevant indicators of patients were detected. Results There were no statistically signiifcant differences in residual renal function, level of lipid, phosphorus and β2-microglobulin of patients among the three groups before treatment. After treated for 6 months, patients’ residual renal function was signiifcantly lower compared to that before treatment, but the decline degree of residual renal function in LFHD group was higher than that in HfHd group and Hd + HP group. after treatment, the patient's blood level of lipids, phosphate and β2-microglobulin in HFHD group and HD + HP group was signiifcantly lower than that in LFHD group, but there was no statistically signiifcant difference between the HFHD group and the HD + HP group. Conclusion After hemodialysis, the residual renal function of patients all declined. But compared with HfHd group and Hd + HP group, there was a lower rate of residual renal function decline in lfHd group, while compared with lfHd group, the treatment of HfHd and Hd + HP can reduce the level of blood lipids, phosphorus and β2-microglobulin levels.
